Sulphomucins and precancerous lesions of the human stomach


Address for correspondence: Dr J.R.Jass, Department of Histopathology, Westminster Medical School, 17 Horseferry Road, London SWIP 2AR.


The histochemical demonstration of sulphomucin secretion by gastric adenomatous polyps and adjacent metaplastic epithelium suggests this glycoprotein may be a marker of premalignant change. A possible relationship with fetal sulphoglycoprotein antigen is discussed.