Are infantile myofibromatosis, congenital fibrosarcoma and congenital haemangiopericytoma histogenetically related?
Article first published online: 3 APR 2007
Volume 26, Issue 1, pages 57–62, January 1995
How to Cite
VARIEND, S., BAX, N.M.A. and GORP, J. V. (1995), Are infantile myofibromatosis, congenital fibrosarcoma and congenital haemangiopericytoma histogenetically related?. Histopathology, 26: 57–62. doi: 10.1111/j.1365-2559.1995.tb00621.x
- Issue published online: 3 APR 2007
- Article first published online: 3 APR 2007
- Date of submission 10 May 1994 Accepted for publication 11 July 1994
- infantile tumours;
Infantile myofibromatosis, congenital fibrosarcoma and congenital/infantile haemangiopericytoma are generally considered distinct entities. Overlapping microscopic features between infantile myofibromatosis and congenital fibrosarcoma, and between infantile myofibromatosis and congenital/infantile haemangiopericytoma, however, have been noted, but not formally reported. This report concerns six neonatal tumours, each exhibiting more than one of the above patterns, supporting a histogenetic relationship among these entities. Immunohistochemistry for smooth muscle actin was found to be useful in the diagnosis of congenital/infantile haemangiopericytoma, and also served to support a histogenetic relationship with the other two entities under consideration.