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References

  • 1
    Hollenberg MD, Compton SJ. International Union of Pharmacology. XXVIII. Proteinase-activated receptors. Pharmacol Rev 2002; 54: 20317.
  • 2
    Déry O, Corvera CU, Steinhoff M, Bunnett NW. Proteinase-activated receptors: novel mechanisms of signaling by serine proteases. Am J Physiol 1998; 274: C142952.
  • 3
    Coughlin SR. Thrombin signalling and protease-activated receptors. Nature 2000; 407: 25864.
  • 4
    Blackhart BD, Emilsson K, Nguyen D, Teng W, Martelli AJ, Nystedt S, Sundelin J, Scarborough RM. Ligand cross-reactivity within the protease-activated receptor family. J Biol Chem 1996; 271: 1646671.
  • 5
    Hollenberg MD, Saifeddine M, Al-Ani B, Kawabata A. Proteinase-activated receptors: structural requirements for activity, receptor cross-reactivity, and receptor selectivity of receptor-activating peptides. Can J Physiol Pharmacol 1997; 75: 83241.
  • 6
    Kawabata A, Saifeddine M, Al-Ani B, Leblond L, Hollenberg MD. Evaluation of proteinase-activated receptor-1 (PAR1) agonists and antagonists using a cultured cell receptor desensitisation assay: activation of PAR2 by PAR1-targeted ligands. J Pharmacol Exper Ther 1999; 288: 35870.
  • 7
    Ishihara H, Connolly AJ, Zeng D, Kahn ML, Zheng YW, Timmons C, Tram T, Coughlin SR. Protease-activated receptor 3 is a second thrombin receptor in humans. Nature 1997; 386: 5026.
  • 8
    Nakanishi-Matsui M, Zheng YW, Sulciner DJ, Weiss EJ, Ludeman MJ, Coughlin SR. PAR3 is a cofactor for PAR4 activation by thrombin. Nature 2000; 404: 60913.
  • 9
    Sambrano GR, Weiss EJ, Zheng YW, Huang W, Coughlin SR. Role of thrombin signalling in platelets in haemostasis and thrombosis. Nature 2001; 413: 748.
  • 10
    Hung DT, Vu TK, Wheaton VI, Ishii K, Coughlin SR. Cloned platelet thrombin receptor is necessary for thrombin-induced platelet activation. J Clin Invest 1992; 89: 13503.
  • 11
    Brass LF, Vassallo RR Jr, Belmonte E, Ahuja M, Cichowski K, Hoxie JA. Structure and function of the human platelet thrombin receptor: studies using monoclonal antibodies directed against a defined domain within the receptor N terminus. J Biol Chem 1992; 267: 137958.
  • 12
    Tordai A, Fenton JW II, Andersen T, Gelfand EW. Functional thrombin receptors on human T lymphoblastoid cells. J Immunol 1993; 150: 487686.
  • 13
    Mari B, Imbert V, Belhacene N et al. Thrombin and thrombin receptor agonist peptide induce early events of T cell activation and synergize with TCR cross-linking for CD69 expression and interleukin 2 production. J Biol Chem 1994; 269: 851723.
  • 14
    Mari B, Guerin S, Far DF, Breitmayer JP, Belhacene N, Peyron JF, Rossi B, Auberger P. Thrombin and trypsin-induced Ca2+ mobilization in human T cell lines through interaction with different protease-activated receptors. FASEB J 1996; 10: 30916.
  • 15
    Bar-Shavit R, Maoz M, Yongjun Y, Groysman M, Dekel I, Katzav S. Signalling pathways induced by protease-activated receptors and integrins in T cells. Immunology 2002; 105: 3546.
  • 16
    Fischer KD, Tedford K, Penninger JM. Vav links antigen-receptor signaling to the actin cytoskeleton. Semin Immunol 1998; 10: 31727.
  • 17
    Turner M, Billadeau DD. VAV proteins as signal integrators for multi-subunit immune-recognition receptors. Nat Rev Immunol 2002; 2: 47686.
  • 18
    Compton SJ, Renaux B, Wijesuriya SJ, Hollenberg MD. Glycosylation and the activation of proteinase-activated receptor 2 (PAR2) by human mast cell tryptase. Br J Pharmacol 2001; 134: 70518.
  • 19
    Saifeddine M, Al-Ani B, Cheng C, Wang L, Hollenberg MD. Rat proteinase-activated receptor-2 (PAR-2). cDNA sequence and activity of receptor-derived peptides in gastric and vascular tissue. Br J Pharmacol 1996; 118: 52130.
  • 20
    Al-Ani B, Saifeddine M, Kawabata A, Renaux B, Mokashi S, Hollenberg MD. Proteinase-activated receptor 2 (PAR2). Development of a ligand-binding assay correlating with activation of PAR2 by PAR1- and PAR2-derived peptide ligands. J Pharmacol Exper Ther 1999; 290: 75360.
  • 21
    Minta A, Kao JP, Tsien RY. Fluorescent indicators for cytosolic calcium based on rhodamine and fluorescein chromophores. J Biol Chem 1989; 264: 81718.
  • 22
    Kao JP, Harootunian AT, Tsien RY. Photochemically generated cytosolic calcium pulses and their detection by fluo-3. J Biol Chem 1989; 264: 817984.
  • 23
    Al-Ani B, Saifeddine M, Kawabata A, Hollenberg MD. Proteinase activated receptor 2: role of extracellular loop 2 for ligand-mediated activation. Br J Pharmacol 1999; 128: 110513.
  • 24
    Compton SJ, Cairns JA, Palmer KJ, Al-Ani B, Hollenberg MD, Walls AF. A polymorphic protease-activated receptor 2 (PAR2) displaying reduced sensitivity to trypsin and differential responses to PAR agonists. J Biol Chem 2000; 275: 3920712.
  • 25
    Kahn ML, Zheng YW, Huang W et al. A dual thrombin receptor system for platelet activation. Nature 1998; 394: 6904.
  • 26
    Vergnolle N, Wallace JL, Bunnett NW, Hollenberg MD. Protease-activated receptors in inflammation, neuronal signaling and pain. Trends Pharmacol Sci 2001; 22: 14652.