• 1
    Stahl PD, Ezekowitz RA. The mannose receptor is a pattern recognition receptor involved in host defense. Curr Opin Immunol 1998; 10:505.
  • 2
    Figdor CG, Van Kooyk Y, Adema GJ. C-type lectin receptors on dendritic cells and Langerhans cells. Nat Rev Immunol 2002; 2:7784.
  • 3
    Jiang W, Swiggard WJ, Heufler C, Peng M, Mirza A, Steinman RM, Nussenzweig MC. The receptor DEC-205 expressed by dendritic cells and thymic epithelial cells is involved in antigen processing. Nature 1995; 375:1515.
  • 4
    McKay PF, Imami N, Johns M et al. The gp200-MR6 molecule which is functionally associated with the IL-4 receptor modulates B cell phenotype and is a novel member of the human macrophage mannose receptor family. Eur J Immunol 1998; 28:407183.
  • 5
    Kato M, Neil TK, Clark GJ, Morris CM, Sorg RV, Hart DN. cDNA cloning of human DEC-205, a putative antigen-uptake receptor on dendritic cells. Immunogenetics 1998; 47:44250.
  • 6
    Swiggard WJ, Mirza A, Nussenzweig MC, Steinman RM. DEC-205, a 205-kDa protein abundant on mouse dendritic cells and thymic epithelium that is detected by the monoclonal antibody NLDC-145: purification, characterization, and N-terminal amino acid sequence. Cell Immunol 1995; 165:30211.
  • 7
    Inaba K, Swiggard WJ, Inaba M, Meltzer J, Mirza A, Sasagawa T, Nussenzweig MC, Steinman RM. Tissue distribution of the DEC-205 protein that is detected by the monoclonal antibody NLDC-145. I. Expression on dendritic cells and other subsets of mouse leukocytes. Cell Immunol 1995; 163:14856.
  • 8
    Von Gaudecker B, Larche M, Schuurman HJ, Ritter MA. Analysis of the fine distribution of thymic epithelial microenvironmental molecules by immuno-electron microscopy. Thymus 1989; 13:18794.
  • 9
    Maruyama K, Akiyama Y, Cheng J, Nara-Ashizawa N, Hojo T, Sasaki K, Yamaguchi K. Hamster DEC-205, its primary structure, tissue and cellular distribution. Cancer Lett 2002; 181:22332.
  • 10
    Gliddon DR, Hope JC, Brooke GP, Howard CJ. DEC-205 expression on migrating dendritic cells in afferent lymph. Immunology 2004; 111:26272.
  • 11
    Kato M, McDonald KJ, Khan S et al. Expression of human DEC-205 (CD205) multilectin receptor on leukocytes. Int Immunol 2006; 18:85769.
  • 12
    De Maagd RA, MacKenzie WA, Schuurman HJ, Ritter MA, Price KM, Broekhuizen R, Kater L. The human thymus microenvironment: heterogeneity detected by monoclonal anti-epithelial cell antibodies. Immunology 1985; 54:74554.
  • 13
    Witmer-Pack MD, Swiggard WJ, Mirza A, Inaba K, Steinman RM. Tissue distribution of the DEC-205 protein that is detected by the monoclonal antibody NLDC-145. II. Expression in situ in lymphoid and nonlymphoid tissues. Cell Immunol 1995; 163:15762.
  • 14
    Larche M, Lamb JR, O'Hehir RE, Imami-Shita N, Zanders ED, Quint DE, Moqbel R, Ritter MA. Functional evidence for a monoclonal antibody that binds to the human IL-4 receptor. Immunology 1988; 65:61722.
  • 15
    Larche M, Lamb JR, Ritter MA. A novel T-lymphocyte molecule that may function in the induction of self-tolerance and MHC-restriction within the human thymic microenvironment. Immunology 1988; 64:1015.
  • 16
    Feinberg H, Park-Snyder S, Kolatkar AR, Heise CT, Taylor ME, Weis WI. Structure of a C-type carbohydrate recognition domain from the macrophage mannose receptor. J Biol Chem 2000; 275:2153948.
  • 17
    Sivolapenko GB, Imami N, Larche M, Epenetos AA, Ritter MA. Enhanced in vivo immunogenicity induced by an antibody to the IL-4 receptor-associated gp200-MR6 molecule. Scand J Immunol 1996; 44:13542.
  • 18
    Mahnke K, Guo M, Lee S, Sepulveda H, Swain SL, Nussenzweig M, Steinman RM. The dendritic cell receptor for endocytosis, DEC-205, can recycle and enhance antigen presentation via major histocompatibility complex class II-positive lysosomal compartments. J Cell Biol 2000; 151:67384.
  • 19
    Tan PH, Beutelspacher SC, Wang YH, McClure MO, Ritter MA, Lombardi G, George AJ. Immunolipoplexes: an efficient, nonviral alternative for transfection of human dendritic cells with potential for clinical vaccination. Mol Ther 2005; 11:790800.
  • 20
    Hawiger D, Inaba K, Dorsett Y et al. Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo. J Exp Med 2001; 194:76979.
  • 21
    Bonifaz L, Bonnyay D, Mahnke K, Rivera M, Nussenzweig MC, Steinman RM. Efficient targeting of protein antigen to the dendritic cell receptor DEC-205 in the steady state leads to antigen presentation on major histocompatibility complex class I products and peripheral CD8+ T cell tolerance. J Exp Med 2002; 196:162738.
  • 22
    Bonifaz LC, Bonnyay DP, Charalambous A et al. In vivo targeting of antigens to maturing dendritic cells via the DEC-205 receptor improves T cell vaccination. J Exp Med 2004; 199:81524.
  • 23
    Altin JG, Van Broekhoven CL, Parish CR. Targeting dendritic cells with antigen-containing liposomes: antitumour immunity. Expert Opin Biol Ther 2004; 4:173547.
  • 24
    Van Broekhoven CL, Parish CR, Demangel C, Britton WJ, Altin JG. Targeting dendritic cells with antigen-containing liposomes: a highly effective procedure for induction of antitumor immunity and for tumor immunotherapy. Cancer Res 2004; 64:435765.
  • 25
    Kato M, Khan S, Gonzalez N, O'Neill BP, McDonald KJ, Cooper BJ, Angel NZ, Hart DN. Hodgkin's lymphoma cell lines express a fusion protein encoded by intergenically spliced mRNA for the multilectin receptor DEC-205 (CD205) and a novel C-type lectin receptor DCL-1. J Biol Chem 2003; 278:3403541.
  • 26
    Larche M, Lamb JR, Ritter MA. p145-MR6: a novel T cell surface molecule with a role in tolerance to self. Adv Exp Med Biol 1988; 237:4137.
  • 27
    Al-Tubuly AA, Luqmani YA, Shousha S, Melcher D, Ritter MA. Differential expression of gp200-MR6 molecule in benign hyperplasia and down-regulation in invasive carcinoma of the breast. Br J Cancer 1996; 74:100511.
  • 28
    Al-Tubuly AA, Spijker R, Pignatelli M, Kirkland SC, Ritter MA. Inhibition of growth and enhancement of differentiation of colorectal carcinoma cell lines by MAb MR6 and IL-4. Int J Cancer 1997; 71:60511.
  • 29
    Kato M, Neil TK, Fearnley DB, McLellan AD, Vuckovic S, Hart DN. Expression of multilectin receptors and comparative FITC-dextran uptake by human dendritic cells. Int Immunol 2000; 12:15119.
  • 30
    Guo M, Gong S, Maric S, Misulovin Z, Pack M, Mahnke K, Nussenzweig MC, Steinman RM. A monoclonal antibody to the DEC-205 endocytosis receptor on human dendritic cells. Hum Immunol 2000; 61:72938.
  • 31
    Palmer DB, Crompton T, Marandi MB, George AJ, Ritter MA. Intrathymic function of the human cortical epithelial cell surface antigen gp200-MR6: single-chain antibodies to evolutionarily conserved determinants disrupt mouse thymus development. Immunology 1999; 96:23645.
  • 32
    Wienke D, MacFadyen JR, Isacke CM. Identification and characterization of the endocytic transmembrane glycoprotein Endo180 as a novel collagen receptor. Mol Biol Cell 2003; 14:3592604.
  • 33
    East L, Rushton S, Taylor ME, Isacke CM. Characterization of sugar binding by the mannose receptor family member, Endo180. J Biol Chem 2002; 277:5046975.
  • 34
    Howard MJ, Isacke CM. The C-type lectin receptor, Endo180, displays internalization and recycling properties distinct from other members of the mannose receptor family. J Biol Chem 2002; 277:3232031.
  • 35
    Sheikh H, Yarwood H, Ashworth A, Isacke CM. Endo180, an endocytic recycling glycoprotein related to the macrophage mannose receptor is expressed on fibroblasts, endothelial cells and macrophages and functions as a lectin receptor. J Cell Sci 2000; 113:102132.
  • 36
    Sallusto F, Cella M, Danieli C, Lanzavecchia A. Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: downregulation by cytokines and bacterial products. J Exp Med 1995; 182:389400.
  • 37
    Diebold SS, Plank C, Cotten M, Wagner E, Zenke M. Mannose receptor-mediated gene delivery into antigen presenting dendritic cells. Somat Cell Mol Genet 2002; 27:6574.
  • 38
    Diebold SS, Kursa M, Wagner E, Cotten M, Zenke M. Mannose polyethylenimine conjugates for targeted DNA delivery into dendritic cells. J Biol Chem 1999; 274:1908794.
  • 39
    Taylor PR, Zamze S, Stillion RJ, Wong SY, Gordon S, Martinez-Pomares L. Development of a specific system for targeting protein to metallophilic macrophages. Proc Natl Acad Sci USA 2004; 101:19638.
  • 40
    Visintin A, Mazzoni A, Spitzer JH, Wyllie DH, Dower SK, Segal DM. Regulation of Toll-like receptors in human monocytes and dendritic cells. J Immunol 2001; 166:24955.
  • 41
    Randolph GJ. Dendritic cell migration to lymph nodes: cytokines, chemokines, and lipid mediators. Semin Immunol 2001; 13:26774.
  • 42
    Hon H, Jacob J. Tracking dendritic cells in vivo: insights into DC biology and function. Immunol Res 2004; 29:6980.
  • 43
    Steinman RM, Inaba K, Turley S, Pierre P, Mellman I. Antigen capture, processing, and presentation by dendritic cells: recent cell biological studies. Hum Immunol 1999; 60:5627.
  • 44
    Pierre P, Turley SJ, Meltzer J, Mirza A, Steinman R, Mellman I. Localization and intracellular transport of MHC class II molecules in bone marrow-derived dendritic cells. Adv Exp Med Biol 1997; 417:17982.
  • 45
    Colmenares M, Puig-Kroger A, Pello OM, Corbi AL, Rivas L. Dendritic cell (DC)-specific intercellular adhesion molecule 3 (ICAM-3)-grabbing nonintegrin (DC-SIGN, CD209), a C-type surface lectin in human DCs, is a receptor for Leishmania amastigotes. J Biol Chem 2002; 277:367669.
  • 46
    Geijtenbeek TB, Engering A, Van Kooyk Y. DC-SIGN, a C-type lectin on dendritic cells that unveils many aspects of dendritic cell biology. J Leukoc Biol 2002; 71:92131.
  • 47
    Bleijs DA, Geijtenbeek TB, Figdor CG, Van Kooyk Y. DC-SIGN and LFA-1: a battle for ligand. Trends Immunol 2001; 22:45763.
  • 48
    Geijtenbeek TB, Krooshoop DJ, Bleijs DA et al. DC-SIGN–ICAM−2 interaction mediates dendritic cell trafficking. Nat Immunol 2000; 1:3537.
  • 49
    Geijtenbeek TB, Torensma R, Van Vliet SJ, Van Duijnhoven GC, Adema GJ, Van Kooyk Y, Figdor CG. Identification of DC-SIGN, a novel dendritic cell-specific ICAM-3 receptor that supports primary immune responses. Cell 2000; 100:57585.
  • 50
    Steinman RM. DC-SIGN: a guide to some mysteries of dendritic cells. Cell 2000; 100:4914.
  • 51
    Small M, Kraal G. In vitro evidence for participation of DEC-205 expressed by thymic cortical epithelial cells in clearance of apoptotic thymocytes. Int Immunol 2003; 15:197203.
  • 52
    Denzer K, Van Eijk M, Kleijmeer MJ, Jakobson E, De Groot C, Geuze HJ. Follicular dendritic cells carry MHC class II-expressing microvesicles at their surface. J Immunol 2000; 165:125965.
  • 53
    Tew JG, Wu J, Qin D, Helm S, Burton GF, Szakal AK. Follicular dendritic cells and presentation of antigen and costimulatory signals to B cells. Immunol Rev 1997; 156:3952.
  • 54
    Tew JG, Wu J, Fakher M, Szakal AK, Qin D. Follicular dendritic cells: beyond the necessity of T-cell help. Trends Immunol 2001; 22:3617.
  • 55
    Magrangeas F, Pitiot G, Dubois S et al. Cotranscription and intergenic splicing of human galactose-1-phosphate uridylyltransferase and interleukin-11 receptor alpha-chain genes generate a fusion mRNA in normal cells. Implication for the production of multidomain proteins during evolution. J Biol Chem 1998; 273:1600510.
  • 56
    Pierre P, Turley SJ, Gatti E et al. Developmental regulation of MHC class II transport in mouse dendritic cells. Nature 1997; 388:78792.
  • 57
    Van Der Wel NN, Sugita M, Fluitsma DM, Cao X, Schreibelt G, Brenner MB, Peters PJ. CD1 and major histocompatibility complex II molecules follow a different course during dendritic cell maturation. Mol Biol Cell 2003; 14:337888.
  • 58
    Klein E, Koch S, Borm B, Neumann J, Herzog V, Koch N, Bieber T. CD83 localization in a recycling compartment of immature human monocyte-derived dendritic cells. Int Immunol 2005; 17:47787.
  • 59
    Geissmann F, Launay P, Pasquier B, Lepelletier Y, Leborgne M, Lehuen A, Brousse N, Monteiro RC. A subset of human dendritic cells expresses IgA Fc receptor (CD89), which mediates internalization and activation upon cross-linking by IgA complexes. J Immunol 2001; 166:34652.
  • 60
    Otero C, Groettrup M, Legler DF. Opposite fate of endocytosed CCR7 and its ligands: recycling versus degradation. J Immunol 2006; 177:231423.
  • 61
    Cella M, Sallusto F, Lanzavecchia A. Origin, maturation and antigen presenting function of dendritic cells. Curr Opin Immunol 1997; 9:106.
  • 62
    Garrett WS, Chen LM, Kroschewski R, Ebersold M, Turley S, Trombetta S, Galan JE, Mellman I. Developmental control of endocytosis in dendritic cells by Cdc42. Cell 2000; 102:32534.