Natural killer cells: integrating diversity with function
Article first published online: 12 JAN 2009
© 2009 Blackwell Publishing Ltd
Volume 126, Issue 4, pages 449–457, April 2009
How to Cite
Cheent, K. and Khakoo, S. I. (2009), Natural killer cells: integrating diversity with function. Immunology, 126: 449–457. doi: 10.1111/j.1365-2567.2009.03045.x
- Issue published online: 2 MAR 2009
- Article first published online: 12 JAN 2009
- Received 2 December 2008; revised 10 December 2008; accepted 10 December 2008.
- NK cells;
The key role of natural killer cells in many aspects of the immune response is now being recognized. The last decade has seen an exponential increase in our understanding of the workings of these cells. Receptor diversity is crucial in allowing natural killer cells to respond effectively to a variety of different pathogens. This article reviews aspects of natural killer cell diversity that combine to generate populations of functional natural killer cells that exist within both the individual and throughout the population at large.