An integrated view of the regulation of NKG2D ligands
Version of Record online: 22 JUN 2009
© 2009 Blackwell Publishing Ltd
Volume 128, Issue 1, pages 1–6, September 2009
How to Cite
Stern-Ginossar, N. and Mandelboim, O. (2009), An integrated view of the regulation of NKG2D ligands. Immunology, 128: 1–6. doi: 10.1111/j.1365-2567.2009.03147.x
- Issue online: 4 AUG 2009
- Version of Record online: 22 JUN 2009
- Received 7 May 2009; revised 6 June 2009; accepted 10 June 2009.
- innate immunity;
- natural killer cells;
NKG2D is one of the best characterized activating receptors and is expressed on natural killer cells and on various T-cell subsets. This receptor recognizes several different ligands that are induced by cellular stresses. In this review, we described the mechanisms controlling the expression of NKG2D ligands, with the emphasis on post-transcriptional and post-translational regulation.