Targeting macrophages in the tumour environment to enhance the efficacy of αOX40 therapy
Article first published online: 2 JUL 2012
© 2012 The Authors. Immunology © 2012 Blackwell Publishing Ltd
Volume 136, Issue 4, pages 437–447, August 2012
How to Cite
Gough, M. J., Killeen, N. and Weinberg, A. D. (2012), Targeting macrophages in the tumour environment to enhance the efficacy of αOX40 therapy. Immunology, 136: 437–447. doi: 10.1111/j.1365-2567.2012.03600.x
- Issue published online: 2 JUL 2012
- Article first published online: 2 JUL 2012
- Accepted manuscript online: 12 MAY 2012 08:54AM EST
- Received 11 January 2012; revised 14 February 2012; accepted 19 April 2012
Figure S1. Analysis of the 50 most a) upregulated and b) downregulated genes in tumor macrophages 7 days following systemic OX40 stimulation. To exclude outliers, genes designated as present in both categories, and genes expressed in αOX40-treated tumor macrophages with an intensity of less than 2 (dotted line) are not shown.
Figure S2. Analysis of expression of genes within the KEGG Antigen Procession and Presentation pathway. Genes are sorted in order of expression, and higher and lower expression genes are shown on different axis to improve visibility. Graphs only show genes designated as present, and expressed at an intensity of greater than 0·5.
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