These authors contributed equally to this work.
Carbohydrate metabolism genes and pathways in insects: insights from the honey bee genome
Article first published online: 27 OCT 2006
Insect Molecular Biology
Volume 15, Issue 5, pages 563–576, October 2006
How to Cite
Kunieda, T., Fujiyuki, T., Kucharski, R., Foret, S., Ament, S. A., Toth, A. L., Ohashi, K., Takeuchi, H., Kamikouchi, A., Kage, E., Morioka, M., Beye, M., Kubo, T., Robinson, G. E. and Maleszka, R. (2006), Carbohydrate metabolism genes and pathways in insects: insights from the honey bee genome. Insect Molecular Biology, 15: 563–576. doi: 10.1111/j.1365-2583.2006.00677.x
Re-use of this article is permitted in accordance with the Creative Commons Deed, Attribution 2·5, which does not permit commercial exploitation.
- Issue published online: 27 OCT 2006
- Article first published online: 27 OCT 2006
- Received 20 March 2006; accepted after revision 2 June 2006.
- insect metabolome;
- lipid metabolism;
- cellulose degradation;
- gene synteny
Carbohydrate-metabolizing enzymes may have particularly interesting roles in the honey bee, Apis mellifera, because this social insect has an extremely carbohydrate-rich diet, and nutrition plays important roles in caste determination and socially mediated behavioural plasticity. We annotated a total of 174 genes encoding carbohydrate-metabolizing enzymes and 28 genes encoding lipid-metabolizing enzymes, based on orthology to their counterparts in the fly, Drosophila melanogaster, and the mosquito, Anopheles gambiae. We found that the number of genes for carbohydrate metabolism appears to be more evolutionarily labile than for lipid metabolism. In particular, we identified striking changes in gene number or genomic organization for genes encoding glycolytic enzymes, cellulase, glucose oxidase and glucose dehydrogenases, glucose-methanol-choline (GMC) oxidoreductases, fucosyltransferases, and lysozymes.