Chikungunya-Wolbachia interplay in Aedes albopictus
Version of Record online: 6 NOV 2008
No claims to original government works. Journal compilation © 2008 The Royal Entomological Society
Insect Molecular Biology
Volume 17, Issue 6, pages 677–684, December 2008
How to Cite
Tortosa, P., Courtiol, A., Moutailler, S., Failloux, A.-B. and Weill, M. (2008), Chikungunya-Wolbachia interplay in Aedes albopictus. Insect Molecular Biology, 17: 677–684. doi: 10.1111/j.1365-2583.2008.00842.x
- Issue online: 6 NOV 2008
- Version of Record online: 6 NOV 2008
- Received 5 June 2008; accepted after revision 18 August 2008.
- Aedes albopictus;
- quantitative PCR
A severe Chikungunya (CHIK) outbreak recently hit several countries of the Indian Ocean. On La Réunion Island, Aedes albopictus was incriminated as the major vector. This mosquito species is naturally co-infected with two distinct strains of the endosymbiont Wolbachia, namely wAlbA and wAlbB, which are increasingly attracting interest as potential tools for vector control. A PCR quantitative assay was developed to investigate Wolbachia/mosquito host interactions. We show that Wolbachia densities are slightly decreased in CHIK virus (CHIKV)-infected females. We measured the impact of CHIKV replication on a lysogenic virus: WO bacteriophage. Our data indicate that WO is sheltered by wAlbB, likely at a single copy per bacteria, and that CHIKV replication is not a physiological stress triggering WO entrance into the lytic cycle.