IAPV, a bee-affecting virus associated with Colony Collapse Disorder can be silenced by dsRNA ingestion

Authors

  • E. Maori,

    1. Robert H. Smith Institute for Plant Sciences and Genetics in Agriculture, Virus Laboratory, Faculty of Agricultural, Food and Environmental Quality Sciences, The Hebrew University of Jerusalem, Rehovot 76100, Israel;
    2. Beeologics LLC, 11800 SW 77th Avenue, Miami, FL 33156; and
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  • N. Paldi,

    1. Beeologics LLC, 11800 SW 77th Avenue, Miami, FL 33156; and
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  • S. Shafir,

    1. B. Triwaks Bee Research Center, Department of Entomology, Faculty of Agricultural, Food and Environmental Quality Sciences, The Hebrew University of Jerusalem, Rehovot 76100, Israel
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  • H. Kalev,

    1. B. Triwaks Bee Research Center, Department of Entomology, Faculty of Agricultural, Food and Environmental Quality Sciences, The Hebrew University of Jerusalem, Rehovot 76100, Israel
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  • E. Tsur,

    1. Robert H. Smith Institute for Plant Sciences and Genetics in Agriculture, Virus Laboratory, Faculty of Agricultural, Food and Environmental Quality Sciences, The Hebrew University of Jerusalem, Rehovot 76100, Israel;
    2. B. Triwaks Bee Research Center, Department of Entomology, Faculty of Agricultural, Food and Environmental Quality Sciences, The Hebrew University of Jerusalem, Rehovot 76100, Israel
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  • E. Glick,

    1. Beeologics LLC, 11800 SW 77th Avenue, Miami, FL 33156; and
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  • I. Sela

    1. Robert H. Smith Institute for Plant Sciences and Genetics in Agriculture, Virus Laboratory, Faculty of Agricultural, Food and Environmental Quality Sciences, The Hebrew University of Jerusalem, Rehovot 76100, Israel;
    2. Beeologics LLC, 11800 SW 77th Avenue, Miami, FL 33156; and
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Ilan Sela, The Hebrew University of Jerusalem, Faculty of Agricultural, Food and Environmental Quality Sciences, Rehovot 76100, Israel. Tel.: +972-8-9489377; Fax: +972-8-9473402, E-mail: sela@agri.huji.ac.il

Abstract

Colony Collapse Disorder (CCD) has been associated with Israeli acute paralysis virus (IAPV). CCD poses a serious threat to apiculture and agriculture as a whole, due to the consequent inability to provide the necessary amount of bees for pollination of critical crops. Here we report on RNAi-silencing of IAPV infection by feeding bees with double-stranded RNA, as an efficient and feasible way of controlling this viral disease. The association of CCD with IAPV is discussed, as well as the potential of controlling CCD.

Ancillary