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Expansion of genes encoding a novel type of dynamin in the genome of the pea aphid, Acyrthosiphon pisum
Article first published online: 23 FEB 2010
DOI: 10.1111/j.1365-2583.2009.00941.x
© 2010 The Royal Entomological Society
Issue
Insect Molecular Biology
Special Issue: The Aphid Genome
Volume 19, Issue Supplement s2, pages 165–173, March 2010
Additional Information
How to Cite
Nakabachi, A. and Miyagishima, S. (2010), Expansion of genes encoding a novel type of dynamin in the genome of the pea aphid, Acyrthosiphon pisum. Insect Molecular Biology, 19: 165–173. doi: 10.1111/j.1365-2583.2009.00941.x
Publication History
- Issue published online: 23 FEB 2010
- Article first published online: 23 FEB 2010
Keywords:
- dynamin;
- aphid;
- gene expansion;
- phylogeny;
- expression
Abstract
Screening of the entire genome of the pea aphid, Acyrthosiphon pisum, detected 15 genes for putative dynamin superfamily proteins – self-assembling large GTPases that are involved in the fission and fusion of membranes. In addition to a single gene each for Dyn, Drp1, and Opa1, orthologues that are common in Metazoa, 12 genes encoding a novel type of dynamin were found. Phylogenetic analyses showed that these novel-class genes are monophyletic. Quantitative reverse transcription-PCR demonstrated that expressions of four novel-class dynamin genes are highly up-regulated in the midgut, through which aphids take in phloem-sap diets and plant viruses. As this type of dynamin is absent from all other fully sequenced organisms, they may function in processes unique to aphids.