Register data on assisted reproductive technology (ART) in Europe including a detailed description of ART in Denmark


Anders Nyboe Andersen, The Fertility Clinic 4071, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen, Denmark. E-mail:


The European Society for Human Reproduction and Embryology (ESHRE) has monitored Assisted Reproduction in Europe since 1997. In 2001, 579 clinics from 23 countries reported 289 690 treatment cycles with: in vitro fertilization (IVF) 120 946, intracytoplasmatisk sperm injection (ICSI) 114 378, frozen embryo replacements (FER) 47 195 and egg donation (ED) 7171. Intrauterine inseminations are less consistently reported, but in 2001, 15 countries reported 67 124 cycles (IUI-H 52 949 and IUI-D 14 185). Data from 2001 showed that in 12 countries, where all clinics reported the in vitro techniques to the register, 829 treatment cycles were performed per million inhabitants. The availability was highest in the Nordic countries (range 975–1923 cycles). The proportion of infants born after ART with in vitro techniques ranged from 0.2% in Latvia to 3.9% in Denmark. In general, the impact of the in vitro techniques on the birth rate is highest in the Nordic countries (range 2.2–3.9%). Denmark is the only country with an established National ART reporting system involving all ART treatments both with the in vitro techniques and intrauterine inseminations. In the year 2002, a total of 20 837 treatment cycles were performed. The result was that 6.2% of all infants were born after assisted reproduction.