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  • Bajpai M., Bal C.S., Tripathi M., Kalaivani M., Gupta A.K. (2007) Prenatally diagnosed unilateral hydronephrosis: prognostic significance of plasma renin activity. J. Urol. 178, 25802584.
  • Basak A., Koch P., Dupelle M. et al. (2001) Inhibitory specificity and potency of proSAAS-derived peptides toward proprotein convertase 1. J. Biol. Chem. 276, 3272032728.
  • Bascands J.L. & Schanstra J.P. (2005) Obstructive nephropathy: insights from genetically engineered animals. Kidney Int. 68, 925937.
  • Benfield M.R., McDonald R.A., Bartosh S., Ho P.L., Harmon W. (2003) Changing trends in pediatric transplantation: 2001 Annual Report of the North American Pediatric Renal Transplant Cooperative Study. Pediatr. Transplant. 7, 321335.
  • Benjannet S., Reudelhuber T., Mercure C., Rondeau N., Chretien M., Seidah N.G. (1992) Proprotein conversion is determined by a multiplicity of factors including convertase processing, substrate specificity, and intracellular environment. Cell type-specific processing of human prorenin by the convertase PC1. J. Biol. Chem. 267, 1141711423.
  • Bor M.V., Shi Y., Sorensen B.S. et al. (2006) Increased TGF-alpha and EGF Receptor mRNA expression in response to neonatal unilateral partial ureter obstruction in rats. Nephron Exp. Nephrol. 104, e76e82.
  • Broadbelt N.V., Stahl P.J., Chen J. et al. (2007) Early upregulation of iNOS mRNA expression and increase in NO metabolites in pressurized renal epithelial cells. Am. J. Physiol. Renal Physiol. 293, F1877F1888.
  • Broadbelt N.V., Chen J., Silver R.B., Poppas D.P., Felsen D. (2009) Pressure activates epidermal growth factor receptor leading to the induction of iNOS via NFkappaB and STAT3 in human proximal tubule cells. Am. J. Physiol. Renal Physiol. 297, F114F124.
  • Burt L.E., Forbes M.S., Thornhill B.A., Kiley S.C., Minor J.J., Chevalier R.L. (2007) Renal vascular endothelial growth factor in neonatal obstructive nephropathy. II. Exogenous VEGF. Am. J. Physiol. Renal Physiol. 292, F168F174.
  • Cachat F., Lange-Sperandio B., Chang A.Y. et al. (2003) Ureteral obstruction in neonatal mice elicits segment-specific tubular cell responses leading to nephron loss. Kidney Int. 63, 564575.
  • Cai Z., Xin J., Pollock D.M., Pollock J.S. (2000) Shear stress-mediated NO production in inner medullary collecting duct cells. Am. J. Physiol. Renal Physiol. 279, F270F274.
  • Carattino M.D., Sheng S., Kleyman T.R. (2004) Epithelial Na+ channels are activated by laminar shear stress. J. Biol. Chem. 279, 41204126.
  • Carev D., Saraga M., Saraga-Babic M. (2008) Expression of intermediate filaments, EGF and TGF-alpha in early human kidney development. J. Mol. Histol. 39, 227235.
  • Carr M.C., Peters C.A., Retik A.B., Mandell J. (1994) Urinary levels of the renal tubular enzyme N-acetyl-beta-D-glucosaminidase in unilateral obstructive uropathy. J. Urol. 151, 442445.
  • Chang C.P., McDill B.W., Neilson J.R. et al. (2004) Calcineurin is required in urinary tract mesenchyme for the development of the pyeloureteral peristaltic machinery. J. Clin. Invest. 113, 10511058.
  • Chen C.O., Park M.H., Forbes M.S. et al. (2007) Angiotensin-converting enzyme inhibition aggravates renal interstitial injury resulting from partial unilateral ureteral obstruction in the neonatal rat. Am. J. Physiol. Renal Physiol. 292, F946F955.
  • Chertin B., Pollack A., Koulikov D. et al. (2006) Conservative treatment of ureteropelvic junction obstruction in children with antenatal diagnosis of hydronephrosis: lessons learned after 16 years of follow-up. Eur. Urol. 49, 734738.
  • Chertin B., Pollack A., Koulikov D. et al. (2009) Does renal function remain stable after puberty in children with prenatal hydronephrosis and improved renal function after pyeloplasty? J. Urol. 182, 18451848.
  • Chevalier R.L. (2008) Chronic partial ureteral obstruction and the developing kidney. Pediatr. Radiol. 38(Suppl. 1), S35S40.
  • Chevalier R.L., Chung K.H., Smith C.D., Ficenec M., Gomez R.A. (1996) Renal apoptosis and clusterin following ureteral obstruction: the role of maturation. J. Urol. 156, 14741479.
  • Chevalier R.L., Goyal S., Wolstenholme J.T., Thornhill B.A. (1998) Obstructive nephropathy in the neonatal rat is attenuated by epidermal growth factor. Kidney Int. 54, 3847.
  • Chevalier R.L., Kim A., Thornhill B.A., Wolstenholme J.T. (1999a) Recovery following relief of unilateral ureteral obstruction in the neonatal rat. Kidney Int. 55, 793807.
  • Chevalier R.L., Thornhill B.A., Wolstenholme J.T., Kim A. (1999b) Unilateral ureteral obstruction in early development alters renal growth: dependence on the duration of obstruction. J. Urol. 161, 309313.
  • Chevalier R.L., Goyal S., Thornhill B.A. (1999c) EGF improves recovery following relief of unilateral ureteral obstruction in the neonatal rat. J. Urol. 162, 15321536.
  • Chevalier R.L., Goyal S., Kim A., Chang A.Y., Landau D., LeRoith D. (2000a) Renal tubulointerstitial injury from ureteral obstruction in the neonatal rat is attenuated by IGF-1. Kidney Int. 57, 882890.
  • Chevalier R.L., Thornhill B.A., Chang A.Y. (2000b) Unilateral ureteral obstruction in neonatal rats leads to renal insufficiency in adulthood. Kidney Int. 58, 19871995.
  • Chevalier R.L., Thornhill B.A., Chang A.Y., Cachat F., Lackey A. (2002) Recovery from release of ureteral obstruction in the rat: relationship to nephrogenesis. Kidney Int. 61, 20332043.
  • Chevalier R.L., Forbes M.S., Thornhill B.A. (2009) Ureteral obstruction as a model of renal interstitial fibrosis and obstructive nephropathy. Kidney Int. 75, 11451152.
  • Chung K.H. & Chevalier R.L. (1996) Arrested development of the neonatal kidney following chronic ureteral obstruction. J. Urol. 155, 11391144.
  • Coleman C.M., Minor J.J., Burt L.E., Thornhill B.A., Forbes M.S., Chevalier R.L. (2007) Angiotensin AT1-receptor inhibition exacerbates renal injury resulting from partial unilateral ureteral obstruction in the neonatal rat. Am. J. Physiol. Renal Physiol. 293, F262F268.
  • Cortell S., Gennari F.J., Davidman M., Bossert W.H., Schwartz W.B. (1973) A definition of proximal and distal tubular compliance. Practical and theoretical implications. J. Clin. Invest. 52, 23302339.
  • Csaicsich D., Greenbaum L.A., Aufricht C. (2004) Upper urinary tract: when is obstruction obstruction? Curr. Opin. Urol. 14, 213217.
  • el-Dahr S.S., Gomez R.A., Gray M.S., Peach M.J., Carey R.M., Chevalier R.L. (1991) Renal nerves modulate renin gene expression in the developing rat kidney with ureteral obstruction. J. Clin. Invest. 87, 800810.
  • Dal Canton A., Stanziale R., Corradi A., Andreucci V.E., Migone L. (1977) Effects of acute ureteral obstruction on glomerular hemodynamics in rat kidney. Kidney Int. 12, 403411.
  • Dal Canton A., Corradi A., Stanziale R., Maruccio G., Migone L. (1979) Effects of 24-hour unilateral ureteral obstruction on glomerular hemodynamics in rat kidney. Kidney Int. 15, 457462.
  • Decramer S., Wittke S., Mischak H. et al. (2006) Predicting the clinical outcome of congenital unilateral ureteropelvic junction obstruction in newborn by urinary proteome analysis. Nat. Med. 12, 398400.
  • Decramer S. & Bascands J.L., Schanstra J.P. (2007) Non-invasive markers of ureteropelvic junction obstruction. World J. Urol. 25, 457465.
  • Dessapt C., Baradez M.O., Hayward A. et al. (2009) Mechanical forces and TGFbeta1 reduce podocyte adhesion through alpha3beta1 integrin downregulation. Nephrol. Dial. Transplant. 24, 26452655.
  • Diamond J.R., Levinson M., Kreisberg R., Ricardo S.D. (1997) Increased expression of decorin in experimental hydronephrosis. Kidney Int. 51, 11331139.
  • Diamond J.R., Kreisberg R., Evans R., Nguyen T.A., Ricardo S.D. (1998) Regulation of proximal tubular osteopontin in experimental hydronephrosis in the rat. Kidney Int. 54, 15011509.
  • Dixon D.L., Barr H.A., Bersten A.D., Doyle I.R. (2008) Intracellular storage of surfactant and proinflammatory cytokines in co-cultured alveolar epithelium and macrophages in response to increasing CO2 and cyclic cell stretch. Exp. Lung Res. 34, 3747.
  • Durvasula R.V. & Shankland S.J. (2005) Mechanical strain increases SPARC levels in podocytes: implications for glomerulosclerosis. Am. J. Physiol. Renal Physiol. 289, F577F584.
  • Durvasula R.V., Petermann A.T., Hiromura K. et al. (2004) Activation of a local tissue angiotensin system in podocytes by mechanical strain. Kidney Int. 65, 3039.
  • Elder J.S., Stansbrey R., Dahms B.B., Selzman A.A. (1995) Renal histological changes secondary to ureteropelvic junction obstruction. J. Urol. 154, 719722.
  • El-Sherbiny M.T., Mousa O.M., Shokeir A.A., Ghoneim M.A. (2002) Role of urinary transforming growth factor-beta1 concentration in the diagnosis of upper urinary tract obstruction in children. J. Urol. 168, 17981800.
  • Endlich N., Kress K.R., Reiser J. et al. (2001) Podocytes respond to mechanical stress in vitro. J. Am. Soc. Nephrol. 12, 413422.
  • Endlich N., Sunohara M., Nietfeld W. et al. (2002) Analysis of differential gene expression in stretched podocytes: osteopontin enhances adaptation of podocytes to mechanical stress. FASEB J. 16, 18501852.
  • Eskild-Jensen A., Christensen H., Lindvig M. et al. (2000) Renal functional outcome in unilateral hydronephrosis in newborn pigs. J. Urol. 163, 18961900.
  • Eskild-Jensen A., Jacobsen L., Christensen H. et al. (2001) Renal function outcome in unilateral hydronephrosis in newborn pigs. II. Function and volume of contralateral kidneys. J. Urol. 165, 205209.
  • Eskild-Jensen A., Frokiaer J., Djurhuus J.C., Jorgensen T.M., Nyengaard J.R. (2002) Reduced number of glomeruli in kidneys with neonatally induced partial ureteropelvic obstruction in pigs. J. Urol. 167, 14351439.
  • Eskild-Jensen A., Paulsen L.F., Wogensen L. et al. (2007a) AT1 receptor blockade prevents interstitial and glomerular apoptosis but not fibrosis in pigs with neonatal induced partial unilateral ureteral obstruction. Am. J. Physiol. Renal Physiol. 292, F1771F1781.
  • Eskild-Jensen A., Thomsen K., Rungo C. et al. (2007b) Glomerular and tubular function during AT1 receptor blockade in pigs with neonatal induced partial ureteropelvic obstruction. Am. J. Physiol. Renal Physiol. 292, F921F929.
  • Essig M., Terzi F., Burtin M., Friedlander G. (2001) Mechanical strains induced by tubular flow affect the phenotype of proximal tubular cells. Am. J. Physiol. Renal Physiol. 281, F751F762.
  • Feldman D.L., Mogelesky T.C., Chou M., Jeng A.Y. (2000) Enhanced expression of renal endothelin-converting enzyme-1 and endothelin-A-receptor mRNA in rats with interstitial fibrosis following ureter ligation. J. Cardiovasc. Pharmacol. 36, S255S259.
  • Fenghua W., Junjie S., Gaoyan D., Jiacong M. (2009) Does intervention in utero preserve the obstructed kidneys of fetal lambs? A histological, cytological, and molecular study. Pediatr. Res. 66, 145148.
  • Fern R.J., Yesko C.M., Thornhill B.A., Kim H.S., Smithies O., Chevalier R.L. (1999) Reduced angiotensinogen expression attenuates renal interstitial fibrosis in obstructive nephropathy in mice. J. Clin. Invest. 103, 3946.
  • Furness 3rd P.D., Maizels M., Han S.W., Cohn R.A., Cheng E.Y. (1999) Elevated bladder urine concentration of transforming growth factor-beta1 correlates with upper urinary tract obstruction in children. J. Urol. 162, 10331036.
  • Garvin J.L. & Hong N.J. (2008) Cellular stretch increases superoxide production in the thick ascending limb. Hypertension 51, 488493.
  • Gottschalk C.W. & Mylle M. (1956) Micropuncture study of pressures in proximal tubules and peritubular capillaries of the rat kidney and their relation to ureteral and renal venous pressures. Am. J. Physiol. 185, 430439.
  • de Graauw M., Tijdens I., Cramer R., Corless S., Timms J.F., van de Water B. (2005) Heat shock protein 27 is the major differentially phosphorylated protein involved in renal epithelial cellular stress response and controls focal adhesion organization and apoptosis. J. Biol. Chem. 280, 2988529898.
  • Grandaliano G., Gesualdo L., Bartoli F. et al. (2000) MCP-1 and EGF renal expression and urine excretion in human congenital obstructive nephropathy. Kidney Int. 58, 182192.
  • Guerin F., Azoulay R., Berrebi D. et al. (2008) Partial unilateral ureteral obstruction in newborn mice: magnetic resonance imaging and pathology studies. J. Urol. 179, 15531563.
  • Guron G., Marcussen N., Nilsson A., Sundelin B., Friberg P. (1999) Postnatal time frame for renal vulnerability to enalapril in rats. J. Am. Soc. Nephrol. 10, 15501560.
  • Han S.W., Lee S.E., Kim J.H., Jeong H.J., Rha K.H., Choi S.K. (1998) Does delayed operation for pediatric ureteropelvic junction obstruction cause histopathological changes? J. Urol. 160, 984988.
  • Hegarty N.J., Watson R.W., Young L.S., O’Neill A.J., Brady H.R., Fitzpatrick J.M. (2002) Cytoprotective effects of nitrates in a cellular model of hydronephrosis. Kidney Int. 62, 7077.
  • Hegarty N.J., Young L.S., O’Neill A.J., Watson R.W., Fitzpatrick J.M. (2003) Endothelin in unilateral ureteral obstruction: vascular and cellular effects. J. Urol. 169, 740744.
  • Heyman S.N., Khamaisi M., Rosen S., Rosenberger C. (2008) Renal parenchymal hypoxia, hypoxia response and the progression of chronic kidney disease. Am. J. Nephrol. 28, 9981006.
  • Hu X., Zhang Y., Cheng D. et al. (2008) Mechanical stress upregulates intercellular adhesion molecule-1 in pulmonary epithelial cells. Respiration 76, 344350.
  • Huang W.Y., Peters C.A., Zurakowski D. et al. (2006) Renal biopsy in congenital ureteropelvic junction obstruction: evidence for parenchymal maldevelopment. Kidney Int. 69, 137143.
  • Jensen M.E., Odgaard E., Christensen M.H., Praetorius H.A., Leipziger J. (2007) Flow-induced [Ca2+]i increase depends on nucleotide release and subsequent purinergic signaling in the intact nephron. J. Am. Soc. Nephrol. 18, 20622070.
  • Jensen A.M., Norregaard R., Topcu S.O., Frokiaer J., Pedersen M. (2009) Oxygen tension correlates with regional blood flow in obstructed rat kidney. J. Exp. Biol. 212, 31563163.
  • Jiang F. (2009) NADPH oxidase in the kidney: a Janus in determining cell fate. Kidney Int. 75, 135137.
  • Josephson S. (1983) Experimental obstructive hydronephrosis in newborn rats. III. Long-term effects on renal function. J. Urol. 129, 396400.
  • Josephson S. & Hemsen A. (1994) Renal tissue endothelin in long-term complete ureteric obstruction in the young rat. Urol. Int. 53, 5761.
  • Just A., Kurtz L., de Wit C., Wagner C., Kurtz A., Arendshorst W.J. (2009) Connexin 40 mediates the tubuloglomerular feedback contribution to renal blood flow autoregulation. J. Am. Soc. Nephrol. 20, 15771585.
  • Kawabe J., Okumura S., Lee M.C., Sadoshima J., Ishikawa Y. (2004) Translocation of caveolin regulates stretch-induced ERK activity in vascular smooth muscle cells. Am. J. Physiol. Heart Circ. Physiol. 286, H1845H1852.
  • Kiley S.C. & Chevalier R.L. (2007) Species differences in renal Src activity direct EGF receptor regulation in life or death response to EGF. Am. J. Physiol. Renal Physiol. 293, F895F903.
  • Kiley S.C., Thornhill B.A., Tang S.S., Ingelfinger J.R., Chevalier R.L. (2003) Growth factor-mediated phosphorylation of proapoptotic BAD reduces tubule cell death in vitro and in vivo. Kidney Int. 63, 3342.
  • Kiley S.C., Thornhill B.A., Belyea B.C. et al. (2005) Epidermal growth factor potentiates renal cell death in hydronephrotic neonatal mice, but cell survival in rats. Kidney Int. 68, 504514.
  • Klein J., Gonzalez J., Duchene J. et al. (2009) Delayed blockade of the kinin B1 receptor reduces renal inflammation and fibrosis in obstructive nephropathy. FASEB J. 23, 134142.
  • Klein J., Gonzalez J., Decramer S. et al. (2010) Protective effects of kinin B1 receptor blockade in glomerulonephritis. J. Am. Soc. Nephrol. In press.
  • Kolb R.J., Woost P.G., Hopfer U. (2004) Membrane trafficking of angiotensin receptor type-1 and mechanochemical signal transduction in proximal tubule cells. Hypertension 44, 352359.
  • Kone B.C. & Baylis C. (1997) Biosynthesis and homeostatic roles of nitric oxide in the normal kidney. Am. J. Physiol. 272, F561F578.
  • Lange-Sperandio B., Cachat F., Thornhill B.A., Chevalier R.L. (2002) Selectins mediate macrophage infiltration in obstructive nephropathy in newborn mice. Kidney Int. 61, 516524.
  • Lange-Sperandio B., Schimpgen K., Rodenbeck B. et al. (2006) Distinct roles of Mac-1 and its counter-receptors in neonatal obstructive nephropathy. Kidney Int. 69, 8188.
  • Lange-Sperandio B., Trautmann A., Eickelberg O. et al. (2007) Leukocytes induce epithelial to mesenchymal transition after unilateral ureteral obstruction in neonatal mice. Am. J. Pathol. 171, 861871.
  • Le Normand L., Buzelin J.M., Bouchot O., Rigaud J., Karam G. (2005) Upper urinary tract: physiology, pathophysiology of obstructions and function assessment. Ann. Urol. (Paris) 39, 3048.
  • Leeb-Lundberg L.M., Marceau F., Muller-Esterl W., Pettibone D.J., Zuraw B.L. (2005) International union of pharmacology. XLV. Classification of the kinin receptor family: from molecular mechanisms to pathophysiological consequences. Pharmacol. Rev. 57, 2777.
  • Leonard E.J. & Yoshimura T. (1990) Human monocyte chemoattractant protein-1 (MCP-1). Immunol. Today 11, 97101.
  • Liapis H., Yu H., Steinhardt G.F. (2000) Cell proliferation, apoptosis, Bcl-2 and Bax expression in obstructed opossum early metanephroi. J. Urol. 164, 511517.
  • Liapis H., Barent B., Steinhardt G.F. (2001) Extracellular matrix in fetal kidney after experimental obstruction. J. Urol. 166, 14331438.
  • Lindoso R.S., Verdoorn K.S., Einicker-Lamas M. (2009) Renal recovery after injury: the role of Pax-2. Nephrol. Dial. Transplant. 24, 26282633.
  • Liu Y. (2010) New insights into epithelial–mesenchymal transition in kidney fibrosis. J. Am. Soc. Nephrol. 21, 212222.
  • Lu C., Ren W., Su X.M., Chen J.Q., Wu S.H., Zhou G.P. (2009) EGF-recruited JunD/c-fos complexes activate CD2AP gene promoter and suppress apoptosis in renal tubular epithelial cells. Gene 433, 5664.
  • Ludwig M.S., Ftouhi-Paquin N., Huang W., Page N., Chakir J., Hamid Q. (2004) Mechanical strain enhances proteoglycan message in fibroblasts from asthmatic subjects. Clin. Exp. Allergy 34, 926930.
  • Lye C.M., Fasano L., Woolf A.S. (2010) Ureter myogenesis: putting Teashirt into context. J. Am. Soc. Nephrol. 21, 2430.
  • Malik R.K., Thornhill B.A., Chang A.Y., Kiley S.C., Chevalier R.L. (2001) Renal apoptosis parallels ceramide content after prolonged ureteral obstruction in the neonatal rat. Am. J. Physiol. Renal Physiol. 281, F56F61.
  • Manucha W. & Valles P.G. (2008) Cytoprotective role of nitric oxide associated with Hsp70 expression in neonatal obstructive nephropathy. Nitric Oxide 18, 204215.
  • Manucha W., Carrizo L., Ruete C., Valles P.G. (2007) Apoptosis induction is associated with decreased NHE1 expression in neonatal unilateral ureteric obstruction. BJU Int. 100, 191198.
  • Matsell D.G. & Tarantal A.F. (2002) Experimental models of fetal obstructive nephropathy. Pediatr. Nephrol. 17, 470476.
  • Mendelsohn C. (2004) Functional obstruction: the renal pelvis rules. J. Clin. Invest. 113, 957959.
  • Mezzano S.A., Ruiz-Ortega M., Egido J. (2001) Angiotensin II and renal fibrosis. Hypertension 38, 635638.
  • Miceli I., Burt D., Tarabra E., Camussi G., Perin P.C., Gruden G. (2010) Stretch reduces nephrin expression via an angiotensin II-AT(1)-dependent mechanism in human podocytes: effect of rosiglitazone. Am. J. Physiol. Renal Physiol. 298, F381F390.
  • Miyajima A., Chen J., Lawrence C. et al. (2000a) Antibody to transforming growth factor-beta ameliorates tubular apoptosis in unilateral ureteral obstruction. Kidney Int. 58, 23012313.
  • Miyajima A., Chen J., Kirman I., Poppas D.P., Darracott Vaughan E.J., Felsen D. (2000b) Interaction of nitric oxide and transforming growth factor-beta1 induced by angiotensin II and mechanical stretch in rat renal tubular epithelial cells. J. Urol. 164, 17291734.
  • Miyajima A., Chen J., Poppas D.P., Vaughan Jr E.D., Felsen D. (2001) Role of nitric oxide in renal tubular apoptosis of unilateral ureteral obstruction. Kidney Int. 59, 12901303.
  • Miyazaki Y., Tsuchida S., Nishimura H. et al. (1998) Angiotensin induces the urinary peristaltic machinery during the perinatal period. J. Clin. Invest. 102, 14891497.
  • Moeller H.B., Praetorius J., Rutzler M.R., Fenton R.A. (2010) Phosphorylation of aquaporin-2 regulates its endocytosis and protein-protein interactions. Proc. Natl Acad. Sci. USA 107, 424429.
  • Mogyorosi A. & Ziyadeh F.N. (1999) What is the role of decorin in diabetic kidney disease? Nephrol. Dial. Transplant. 14, 10781081.
  • Mure P.Y., Gelas T., Dijoud F. et al. (2006a) Complete unilateral ureteral obstruction in the fetal lamb. Part II: Long-term outcomes of renal tissue development. J. Urol. 175, 15481558.
  • Mure P.Y., Gelas T., Benchaib M. et al. (2006b) Complete unilateral ureteral obstruction in the fetal lamb. Part I: long-term outcomes of renal hemodynamics and anatomy. J. Urol. 175, 15411547.
  • Murer L., Benetti E., Centi S. et al. (2006) Clinical and molecular markers of chronic interstitial nephropathy in congenital unilateral ureteropelvic junction obstruction. J. Urol. 176, 26682673. discussion 2673.
  • Nguyen H.T. & Kogan B.A. (1998) Renal hemodynamic changes after complete and partial unilateral ureteral obstruction in the fetal lamb. J. Urol. 160, 10631069.
  • Nguyen H.T., Thomson A.A., Kogan B.A., Baskin L.S., Cunha G.R. (1999a) Growth factor expression in the obstructed developing and mature rat kidney. Lab. Invest. 79, 171184.
  • Nguyen H.T., Thomson A.A., Kogan B.A., Baskin L.S., Cunha G.R. (1999b) Expression of the Wnt gene family during late nephrogenesis and complete ureteral obstruction. Lab. Invest. 79, 647658.
  • Nguyen H.T., Bride S.H., Badawy A.B. et al. (2000) Heparin-binding EGF-like growth factor is up-regulated in the obstructed kidney in a cell- and region-specific manner and acts to inhibit apoptosis. Am. J. Pathol. 156, 889898.
  • Nishimura H., Yerkes E., Hohenfellner K. et al. (1999) Role of the angiotensin type 2 receptor gene in congenital anomalies of the kidney and urinary tract, CAKUT, of mice and men. Mol. Cell 3, 110.
  • Norwood V.F., Carey R.M., Geary K.M., Jose P.A., Gomez R.A., Chevalier R.L. (1994) Neonatal ureteral obstruction stimulates recruitment of renin-secreting renal cortical cells. Kidney Int. 45, 13331339.
  • Okada H., Watanabe Y., Kikuta T. et al. (2004) Bradykinin decreases plasminogen activator inhibitor-1 expression and facilitates matrix degradation in the renal tubulointerstitium under angiotensin-converting enzyme blockade. J. Am. Soc. Nephrol. 15, 24042413.
  • Ortiz P.A., Hong N.J., Garvin J.L. (2004) Luminal flow induces eNOS activation and translocation in the rat thick ascending limb. Am. J. Physiol. Renal. Physiol. 287, F274F280.
  • Oudin S. & Pugin J. (2002) Role of MAP kinase activation in interleukin-8 production by human BEAS-2B bronchial epithelial cells submitted to cyclic stretch. Am. J. Respir. Cell Mol. Biol. 27, 107114.
  • Ozaki S., Kaneko S., Podyma-Inoue K.A., Yanagishita M., Soma K. (2005) Modulation of extracellular matrix synthesis and alkaline phosphatase activity of periodontal ligament cells by mechanical stress. J. Periodontal. Res. 40, 110117.
  • Padovano V., Massari S., Mazzucchelli S., Pietrini G. (2009) PKC induces internalization and retention of the EAAC1 glutamate transporter in recycling endosomes of MDCK cells. Am. J. Physiol. Cell Physiol. 297, C835C844.
  • Pesquero J.B., Araujo R.C., Heppenstall P.A. et al. (2000) Hypoalgesia and altered inflammatory responses in mice lacking kinin B1 receptors. Proc. Natl Acad. Sci. USA 97, 81408145.
  • Petermann A.T., Hiromura K., Blonski M. et al. (2002) Mechanical stress reduces podocyte proliferation in vitro. Kidney Int. 61, 4050.
  • Petermann A.T., Pippin J., Durvasula R. et al. (2005) Mechanical stretch induces podocyte hypertrophy in vitro. Kidney Int. 67, 157166.
  • Peters C.A. (1997) Obstruction of the fetal urinary tract. J. Am. Soc. Nephrol. 8, 653663.
  • Peters C.A. (2001) Animal models of fetal renal disease. Prenat. Diagn. 21, 917923.
  • Praetorius H.A., Frokiaer J., Leipziger J. (2005) Transepithelial pressure pulses induce nucleotide release in polarized MDCK cells. Am. J. Physiol. Renal Physiol. 288, F133F141.
  • Preisig P.A. (1992) Luminal flow rate regulates proximal tubule H-HCO3 transporters. Am. J. Physiol. 262, F47F54.
  • Qin X.S., Tsukaguchi H., Shono A., Yamamoto A., Kurihara H., Doi T. (2009) Phosphorylation of nephrin triggers its internalization by raft-mediated endocytosis. J. Am. Soc. Nephrol. 20, 25342545.
  • Quinlan M.R., Docherty N.G., Watson R.W., Fitzpatrick J.M. (2008) Exploring mechanisms involved in renal tubular sensing of mechanical stretch following ureteric obstruction. Am. J. Physiol. Renal Physiol. 295, F1F11.
  • Ramstrom C., Chapman H., Viitanen T. et al. (2010) Regulation of HERG (KCNH2) potassium channel surface expression by diacylglycerol. Cell. Mol. Life Sci. 67, 157169.
  • Ricardo S.D., Ding G., Eufemio M., Diamond J.R. (1997) Antioxidant expression in experimental hydronephrosis: role of mechanical stretch and growth factors. Am. J. Physiol. 272, F789F798.
  • Ricardo S.D., Franzoni D.F., Roesener C.D., Crisman J.M., Diamond J.R. (2000) Angiotensinogen and AT(1) antisense inhibition of osteopontin translation in rat proximal tubular cells. Am. J. Physiol. Renal Physiol. 278, F708F716.
  • Robert B. & Abrahamson D.R. (2001) Control of glomerular capillary development by growth factor/receptor kinases. Pediatr. Nephrol. 16, 294301.
  • Rohatgi R. & Flores D. (2010) Intratubular hydrodynamic forces influence tubulointerstitial fibrosis in the kidney. Curr. Opin. Nephrol. Hypertens. 19, 6571.
  • Rosen S., Peters C.A., Chevalier R.L., Huang W.Y. (2008) The kidney in congenital ureteropelvic junction obstruction: a spectrum from normal to nephrectomy. J. Urol. 179, 12571263.
  • Roth K.S., Koo H.P., Spottswood S.E., Chan J.C. (2002) Obstructive uropathy: an important cause of chronic renal failure in children. Clin. Pediatr. (Phila) 41, 309314.
  • Ruster C. & Wolf G. (2006) Renin-angiotensin-aldosterone system and progression of renal disease. J. Am. Soc. Nephrol. 17, 29852991.
  • Saba J.D. & Obeid L.M., Hannun Y.A. (1996) Ceramide: an intracellular mediator of apoptosis and growth suppression. Philos. Trans. R. Soc. Lond. B Biol. Sci. 351, 233240. discussion 240–241.
  • Saifudeen Z., Dipp S., Stefkova J., Yao X., Lookabaugh S., El-Dahr S.S. (2009) p53 regulates metanephric development. J. Am. Soc. Nephrol. 20, 23282337.
  • Satlin L.M., Sheng S., Woda C.B., Kleyman T.R. (2001) Epithelial Na(+) channels are regulated by flow. Am. J. Physiol. Renal Physiol. 280, F1010F1018.
  • Sato M., Muragaki Y., Saika S., Roberts A.B., Ooshima A. (2003) Targeted disruption of TGF-beta1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction. J. Clin. Invest. 112, 14861494.
  • Schanstra J.P., Neau E., Drogoz P. et al. (2002) In vivo bradykinin B2 receptor activation reduces renal fibrosis. J. Clin. Invest. 110, 371379.
  • Schelling J.R. & Abu Jawdeh B.G. (2008) Regulation of cell survival by Na+/H+ exchanger-1. Am. J. Physiol. Renal Physiol. 295, F625F632.
  • Schrijvers B.F., Flyvbjerg A., De Vriese A.S. (2004) The role of vascular endothelial growth factor (VEGF) in renal pathophysiology. Kidney Int. 65, 20032017.
  • Seccia T.M., Belloni A.S., Guidolin D. et al. (2006) The renal antifibrotic effects of angiotensin-converting enzyme inhibition involve bradykinin B2 receptor activation in angiotensin II-dependent hypertension. J. Hypertens. 24, 14191427.
  • Sekine T., Miura K., Takahashi K., Igarashi T. (2009) Children’s toxicology from bench to bed--Drug-induced renal injury (1): The toxic effects of ARB/ACEI on fetal kidney development. J. Toxicol. Sci. 34(Suppl. 2), SP245SP250.
  • Shi Y., Li C., Thomsen K. et al. (2004a) Neonatal ureteral obstruction alters expression of renal sodium transporters and aquaporin water channels. Kidney Int. 66, 203215.
  • Shi Y., Pedersen M., Li C. et al. (2004b) Early release of neonatal ureteral obstruction preserves renal function. Am. J. Physiol. Renal Physiol. 286, F1087F1099.
  • Shokeir A.A. & Taha M.A. (2009) Role of urinary tubular enzymes in evaluation of children with ureteropelvic junction narrowing under conservative management. Urology 73, 10161020.
  • Silverstein D.M., Travis B.R., Thornhill B.A. et al. (2003a) Altered expression of immune modulator and structural genes in neonatal unilateral ureteral obstruction. Kidney Int. 64, 2535.
  • Silverstein D.M., Thornhill B.A., Leung J.C. et al. (2003b) Expression of connexins in the normal and obstructed developing kidney. Pediatr. Nephrol. 18, 216224.
  • Sipos A., Vargas S.L., Toma I., Hanner F., Willecke K., Peti-Peterdi J. (2009) Connexin 30 deficiency impairs renal tubular ATP release and pressure natriuresis. J. Am. Soc. Nephrol. 20, 17241732.
  • Steinhardt G.F., Liapis H., Phillips B., Vogler G., Nag M., Yoon K.W. (1995) Insulin-like growth factor improves renal architecture of fetal kidneys with complete ureteral obstruction. J. Urol. 154, 690693.
  • Stock J.A., Krous H.F., Heffernan J., Packer M., Kaplan G.W. (1995) Correlation of renal biopsy and radionuclide renal scan differential function in patients with unilateral ureteropelvic junction obstruction. J. Urol. 154, 716718.
  • Taha M.A., Shokeir A.A., Osman H.G., Abd el-Aziz Ael A., Farahat S.E. (2007a) Diagnosis of ureteropelvic junction obstruction in children: role of endothelin-1 in voided urine. Urology 69, 560564. discussion 564–565.
  • Taha M.A., Shokeir A.A., Osman H.G., Abd El-Aziz Ael A., Farahat S.E. (2007b) Pelvi-ureteric junction obstruction in children: the role of urinary transforming growth factor-beta and epidermal growth factor. BJU Int. 99, 899903.
  • Takenaka T., Inoue T., Kanno Y. et al. (2008) Expression and role of connexins in the rat renal vasculature. Kidney Int. 73, 415422.
  • Tanaka T. & Nangaku M. (2010) The role of hypoxia, increased oxygen consumption, and hypoxia-inducible factor-1 alpha in progression of chronic kidney disease. Curr. Opin. Nephrol. Hypertens. 19, 4350.
  • Thornhill B.A., Burt L.E., Chen C., Forbes M.S., Chevalier R.L. (2005) Variable chronic partial ureteral obstruction in the neonatal rat: a new model of ureteropelvic junction obstruction. Kidney Int. 67, 4252.
  • Thornhill B.A., Forbes M.S., Marcinko E.S., Chevalier R.L. (2007) Glomerulotubular disconnection in neonatal mice after relief of partial ureteral obstruction. Kidney Int. 72, 11031112.
  • Tian S., Ding G., Jia R., Chu G. (2006) Tubulointerstitial macrophage accumulation is regulated by sequentially expressed osteopontin and macrophage colony-stimulating factor: implication for the role of atorvastatin. Mediators Inflamm. 2006, 12919.
  • Topcu S.O., Pedersen M., Norregaard R. et al. (2007) Candesartan prevents long-term impairment of renal function in response to neonatal partial unilateral ureteral obstruction. Am. J. Physiol. Renal Physiol. 292, F736F748.
  • Trougakos I.P. & Gonos E.S. (2006) Regulation of clusterin/apolipoprotein J, a functional homologue to the small heat shock proteins, by oxidative stress in ageing and age-related diseases. Free Radic. Res. 40, 13241334.
  • Valles P.G., Pascual L., Manucha W., Carrizo L., Ruttler M. (2003) Role of endogenous nitric oxide in unilateral ureteropelvic junction obstruction in children. Kidney Int. 63, 11041115.
  • Valles P.G., Manucha W., Carrizo L., Vega Perugorria J., Seltzer A., Ruete C. (2007) Renal caveolin-1 expression in children with unilateral ureteropelvic junction obstruction. Pediatr. Nephrol. 22, 237248.
  • Villegas G., Lange-Sperandio B., Tufro A. (2005) Autocrine and paracrine functions of vascular endothelial growth factor (VEGF) in renal tubular epithelial cells. Kidney Int. 67, 449457.
  • Vlahakis N.E., Schroeder M.A., Limper A.H., Hubmayr R.D. (1999) Stretch induces cytokine release by alveolar epithelial cells in vitro. Am. J. Physiol. 277, L167L173.
  • Wang G., Topcu S.O., Ring T. et al. (2009) Age-dependent renal expression of acid-base transporters in neonatal ureter obstruction. Pediatr. Nephrol. 24, 14871500.
  • Wang Y., Maciejewski B.S., Drouillard D. et al. (2010) A role for caveolin-1 in mechanotransduction of fetal type II epithelial cells. Am. J. Physiol. Lung Cell. Mol. Physiol. 298, 775783.
  • Wen J.G., Frokiaer J., Zhao J.B., Ringgaard S., Jorgensen T.M., Djurhuus J.C. (2002) Severe partial ureteric obstruction in newborn rats can produce renal dysplasia. BJU Int. 89, 740745.
  • Wen J.G., Wang G.X., Chen Y. et al. (2009) Long-term EGF treatment partially prevents reduction of renal blood flow in response to neonatally induced partial unilateral ureteral obstruction. Nephron. Exp. Nephrol. 111, e51e59.
  • Wilda M., Bachner D., Just W. et al. (2000) A comparison of the expression pattern of five genes of the family of small leucine-rich proteoglycans during mouse development. J. Bone Miner. Res. 15, 21872196.
  • Wilson D.R. (1980) Pathophysiology of obstructive nephropathy. Kidney Int. 18, 281292.
  • Wolak T., Kim H., Ren Y., Kim J., Vaziri N.D., Nicholas S.B. (2009) Osteopontin modulates angiotensin II-induced inflammation, oxidative stress, and fibrosis of the kidney. Kidney Int. 76, 3243.
  • Wu F., Yao H., Bader A. et al. (2007) Decorin gene transfer inhibited the expression of TGFbeta1 and ECM in rat mesangial cells. Eur. J. Med. Res. 12, 360368.
  • Wu H., Wang S., Xue A. et al. (2008) Overexpression of decorin induces apoptosis and cell growth arrest in cultured rat mesangial cells in vitro. Nephrology (Carlton) 13, 607615.
  • Wynn T.A. (2008) Cellular and molecular mechanisms of fibrosis. J. Pathol. 214, 199210.
  • Xie Y., Nishi S., Iguchi S. et al. (2001) Expression of osteopontin in gentamicin-induced acute tubular necrosis and its recovery process. Kidney Int. 59, 959974.
  • Yamamoto H., Teramoto H., Uetani K., Igawa K., Shimizu E. (2001) Stretch induces a growth factor in alveolar cells via protein kinase. Respir. Physiol. 127, 105111.
  • Yamazaki T., Komuro I., Kudoh S. et al. (1998) Role of ion channels and exchangers in mechanical stretch-induced cardiomyocyte hypertrophy. Circ. Res. 82, 430437.
  • Yang S.P., Woolf A.S., Quinn F., Winyard P.J. (2001) Deregulation of renal transforming growth factor-beta1 after experimental short-term ureteric obstruction in fetal sheep. Am. J. Pathol. 159, 109117.
  • Yang Y., Hou Y., Wang C.L., Ji S.J. (2006) Renal expression of epidermal growth factor and transforming growth factor-beta1 in children with congenital hydronephrosis. Urology 67, 817821; discussion 821–822.
  • Yiee J.H., Johnson-Welch S., Baker L.A., Wilcox D.T. (2010) Histologic Differences Between Extrinsic and Intrinsic Ureteropelvic Junction Obstruction. Urology 76, 181184.
  • Yoo K.H., Norwood V.F., el-Dahr S.S., Yosipiv I., Chevalier R.L. (1997) Regulation of angiotensin II AT1 and AT2 receptors in neonatal ureteral obstruction. Am. J. Physiol. 273, R503R509.
  • Yoo K.H., Thornhill B.A., Forbes M.S., Chevalier R.L. (2006a) Compensatory renal growth due to neonatal ureteral obstruction: implications for clinical studies. Pediatr. Nephrol. 21, 368375.
  • Yoo K.H., Thornhill B.A., Forbes M.S. et al. (2006b) Osteopontin regulates renal apoptosis and interstitial fibrosis in neonatal chronic unilateral ureteral obstruction. Kidney Int. 70, 17351741.
  • Yoo K.H., Thornhill B.A., Forbes M.S., Chevalier R.L. (2010) Inducible nitric oxide synthase modulates hydronephrosis following partial or complete unilateral ureteral obstruction in the neonatal mouse. Am. J. Physiol. Renal Physiol. 298, F62F71.
  • Zeng F., Singh A.B., Harris R.C. (2009) The role of the EGF family of ligands and receptors in renal development, physiology and pathophysiology. Exp. Cell Res. 315, 602610.
  • Zhang P.L., Peters C.A., Rosen S. (2000) Ureteropelvic junction obstruction: morphological and clinical studies. Pediatr. Nephrol. 14, 820826.