SUMMARY— The acceleration of freeze-drying rates using spiked plates was observed experimentally and found to reduce overall drying times by as much as 24 hr. Experiments were conducted using different spike diameters, sample thickness, spike materials and heater plate temperatures. Weight loss and temperature profiles were obtained as a function of drying times. These experimental results were used to develop a simplified mathematical model for predicting drying rates which will be of use to the designer of spiked-plate freeze-drying systems. Results obtained using the mathematical model indicate spike diameter, spike spacing and plate temperature have significant effect on the drying rate, whereas sample thickness and spike material are not significant.