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ABSTRACT

In short-term studies, substitution of dietary sucrose (50%) with wheat flour or its starch component caused, in hypercholesteremic young male rats, an appreciable decrease in fasting serum cholesterol levels; patent flour showed a more pronounced such effect than high-extraction flour. Liver cholesterol levels were also greatly reduced in flour-fed rats. Substitution of dietary sucrose with wheat gluten substantially reduced the liver accumulation of cholesterol, triglycerides and phospholipids but lowering effect on serum lipids was mostly observed under the condition of partial, rather than complete, substitution of sucrose with gluten.