Meat Science Research Lab., Agricultural Marketing Research Institute ARS, USDA, Beltsville, MD 20705
ADENYLATE CYCLASE AND CYCLIC 3′,5′-NUCLEOTIDE PHOSPHODIESTERASE ACTIVITIES IN MUSCLES FROM STRESS-SUSCEPTIBLE AND CONTROL PIGS
Article first published online: 25 AUG 2006
Journal of Food Science
Volume 42, Issue 1, pages 111–112, January 1977
How to Cite
ONO, K., TOPEL, D. G. and ALTHEN, T. G. (1977), ADENYLATE CYCLASE AND CYCLIC 3′,5′-NUCLEOTIDE PHOSPHODIESTERASE ACTIVITIES IN MUSCLES FROM STRESS-SUSCEPTIBLE AND CONTROL PIGS. Journal of Food Science, 42: 111–112. doi: 10.1111/j.1365-2621.1977.tb01231.x
Prisented at the 36th Annual Meeting of the Institute of Food Technologists, Anaheim, June 6–9, 1976.
Mention of specific trade names and oompanies is for identification purposes only and does not imply endorsement by the U.S. Government.
- Issue published online: 25 AUG 2006
- Article first published online: 25 AUG 2006
- Ms received 3/31/76; revised 8/6/76; accepted 8/10/76.
Recent results from our laboratory indicate that muscles obtained at 3 min postmortem from stress susceptible (SS) pigs have slightly higher levels of cyclic AMP (c-AMP) than muscles from control (C) pigs. Since c-AMP affects glycogenolysis and an abnormality of this process is a characteristic of SS pigs, this research was conducted to determine whether the elevation in c-AMP level is due to an increase in the rate of synthesis or to a decrease in the rate of c-AMP degradation. Specific activities of adenylate cyclase, the synthetic enzyme, were 146 f 62 (SD) for SS and 168 ± 46 pmoles/min/mg protein for-C; this difference was not significant (P = 0.05). Specific activities of cyclic 3′,5′-nucleo-tide phosphodiesterase, the degradative enzyme, were 403 ± 58 for SS and 415 ± 66 pmoles/min/mg protein for C; this difference was not significant (P = 0.05).