The medical and nursing literature suggests measurement of attitude (feelings and beliefs) of clients with schizophrenia may be possible. This paper reports a study by the author using Fishbein's expectancy-value model to measure attitude toward taking medication and reflects on significant implications of both the research reported in the literature and the author's study. How symptoms of schizophrenia affect communication, attitude toward treatment, attitude toward taking medication, and clinical implications of measuring the attitude of clients with schizophrenia toward taking medication are discussed.