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The following supplementary material is available for this article.

Appendix S1. Detailed methods and results of the randomised badger culling trial.

Fig. S1. Locations of proactive culling, reactive culling and no culling areas of the RBCT.

Table S1. Dates of proactive culls by triplet and cull number.

Table S2. Approximate dates of reactive culling, by triplet and badger year.

Table S3. Numbers of badgers included in analyses.

Table S4. Numbers of cattle herds included in analyses presented from proactive areas.

Table S5. Clustering of M. bovis infection within badger populations.

Table S6. Median distances to the nearest infected badger or TB-affected herd, measured from badgers and herds with and without evidence of infection, in proactive areas.

Table S7. Robustness of the linear relationship between cull number and M. bovis clustering in badgers.

Table S8. Effect of lesions on M. bovis clustering within badger populations.

Table S9. Clustering of infection within cattle populations in proactive areas.

Table S10. Clustering of infection within cattle populations in proactive areas, excluding contiguous tests.

Table S11. Analysis of the linear relationship between cull number and M. bovis clustering in cattle inside proactive areas.

Table S12. Clustering of M. bovis infections in cattle in proactive areas, accounting for overlapping observation periods.

Table S13. Effect of lesions on clustering of infections in cattle populations in proactive areas.

Table S14. Clustering of M. bovis infection within cattle populations in survey-only areas.

Table S15. Clustering of M. bovis infection within cattle populations ≤ 2 km outside proactive areas.

Table S16. Clustering of M. bovis infection within cattle populations in reactive areas.

Table S17. Spatial association of M. bovis infection in cattle and badgers in proactive areas.

Table S18. Robustness of the linear relationship between cull number and spatial association of M. bovis infections in cattle and badgers.

Table S19. Spatial association between lesioned badgers in proactive areas and infected cattle.

Table S20. Spatial association of lesioned cattle and infected badgers in proactive areas.

Table S21. Spatial associations of M. bovis spoligoypes within and between badger and cattle populations, on successive proactive badger culls.

Table S22. Median distances to the nearest badger or herd with the same, or a different, spoligotype as the index animal.

This material is available as part of the online article from: http://www.blackwell-synergy.com/doi/full/10.1111/j.1365-2664.2007.01372.x

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