The protective activity of tea against infection by Vibrio cholerae O1

Authors


Department of Bacteriology and Immunology, Showa University School of Medicine, Shinagawa-ku, Tokyo 142, Japan

Abstract

Extracts of black tea exhibited bactericidal activity against Vibrio cholerae O1. The tea extract inhibited the haemolysin activity of V. cholerae O1, El Tor and the morphological changes of Chinese hamster ovary cells induced by cholera toxin. Tea extract also reduced fluid accumulation induced by cholera toxin in sealed adult mice and by V. cholerae O1 in ligated intestinal loops of rabbits. These findings suggest that tea has protective activity against V. cholerae O1.

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