Prevention of intestinal Campylobacter jejuni colonization in broilers by combinations of in-feed organic acids
Article first published online: 12 MAY 2010
© 2010 The Authors. Journal compilation © 2010 The Society for Applied Microbiology
Journal of Applied Microbiology
Volume 109, Issue 4, pages 1265–1273, October 2010
How to Cite
Skånseng, B., Kaldhusdal, M., Moen, B., Gjevre, A.-G., Johannessen, G.S., Sekelja, M., Trosvik, P. and Rudi, K. (2010), Prevention of intestinal Campylobacter jejuni colonization in broilers by combinations of in-feed organic acids. Journal of Applied Microbiology, 109: 1265–1273. doi: 10.1111/j.1365-2672.2010.04766.x
- Issue published online: 16 SEP 2010
- Article first published online: 12 MAY 2010
- 2010/0151: received 27 January 2010, revised and accepted 3 April 2010
- Campylobacter jejuni;
- formic acid;
- infection model;
- potassium sorbate;
Aim: We have tested the effect of various combinations of formic acid and sorbate on Campylobacter jejuni colonization in broiler chickens to reduce the colonization of this zoonotic pathogen in broiler chicken flocks.
Methods and Results: Chickens were offered feed supplemented with different concentrations and combinations of formic acid and/or potassium sorbate. We found little or no effect on the Camp. jejuni colonization levels in chickens that were given feed supplemented with formic acid alone. A combination of 1·5% formic acid and 0·1% sorbate reduced the colonization of Camp. jejuni significantly, while a concentration of 2·0% formic acid in combination with 0·1% sorbate prevented Camp. jejuni colonization in chickens. This inhibition was replicated in two independent trials with a combination of three different Camp. jejuni strains.
Conclusions: Our results show a novel and promising intervention strategy to reduce the incidence of Camp. jejuni in poultry products and to obtain safer food.
Significance and Impact of the Study: To ensure food safety, a reduction of the carcass contamination with Camp. jejuni through reduced colonization of this pathogen in broiler chicken flocks is important. A range of organic acids as additives in feed and drinking water have already been evaluated for this purpose. However, no studies have yet shown a complete inhibition of Camp. jejuni colonization in broiler chickens.