Lack of association of migraine with coronary vasospasm
Article first published online: 4 AUG 2009
1991 Blackwell Publishing Ltd
Journal of Internal Medicine
Volume 230, Issue 5, pages 455–458, November 1991
How to Cite
PLIML, W., KOMMISSARI, I., PFAFFENRATH, V. and VON ARNIM, T. (1991), Lack of association of migraine with coronary vasospasm. Journal of Internal Medicine, 230: 455–458. doi: 10.1111/j.1365-2796.1991.tb00472.x
- Issue published online: 4 AUG 2009
- Article first published online: 4 AUG 2009
- Received 22 March 1991, accepted 22 May 1991.
- ambulatory electrocardiography;
- coronary vasospasm;
- variant angina
Abstract. Previous reports have found an association between coronary vasospasm and migraine. It has been speculated that migraine and variant angina might be manifestations of a generalized vasospastic disorder. To investigate this hypothesis, 74 patients with frequent attacks of migraine were studied using 24-h continuous ambulatory electrocardiography to identify the presence of coronary vasospasm. Control groups consisted of 19 patients with tension headaches, and 38 healthy individuals. All subjects were free of heart disease. One patient in the migraine group and one patient in the control group had symptomless episodes of ST-segment depression not indicative of coronary vasospasm. Our data do not support the hypothesis that migraine and variant angina are components of a generalized vasospastic disorder.