• 1
    Evengard B, Schacterle RS, Komaroff AL. Chronic fatigue syndrome: new insights and old ignorance. J Intern Med 1999; 246: 45569.
  • 2
    Fukuda K, Strauss SE, Hickie I et al. The chronic fatigue syndrome: a comprehensive approach to its definition and study. Ann Intern Med 1994; 121: 9539.
  • 3
    Kent-Braun JA, Sharma KR, Weiner MW, Massie B, Miller RG. Central basis of muscle fatigue in chronic fatigue syndrome. Neurology 1993; 43: 12431.
  • 4
    Lloyd AR, Gandevia SC, Hales JP. Muscle performance, voluntary activation, twitch properties and perceived efforts in normal subjects and patients with the chronic fatigue syndrome. Brain 1991; 114: 8598.
  • 5
    Stokes MJ, Cooper RG, Edwards RH. Normal muscle strength and fatigability in patients with effort syndromes. Brit Med J 1988; 297: 10147.
  • 6
    Samii A, Wassermann EM, Ikoma K et al. Decreased postexercise facilitation of motor evoked potentials in patients with chronic fatigue syndrome or depression. Neurology 1996; 47: 14104.
  • 7
    Paul L, Wood L, Behan WM, Maclaren WM. Demonstration of delayed recovery from fatiguing exercise in chronic fatigue syndrome. Eur J Neurol 1999; 6: 639.
  • 8
    Fulle S, Belia S, Vecchiet J, Morabito C, Vecchiet L, Fano G. Modification of the functional capacity of sarcoplasmic reticulum membranes in patients suffering from chronic fatigue syndrome. Neuromuscul Disord 2003; 13: 47984.
  • 9
    De Becker P, Roeykens J, Reynders M, McGregor N, De Meirleir K. Exercise capacity in chronic fatigue syndrome. Arch Intern Med 2000; 27: 32707.
  • 10
    Riley MS, O'Brien CJ, McCluskey DR, Bell NP, Nicholls DP. Aerobic work capacity in patients with chronic fatigue syndrome. Brit Med J 1990; 27: 9536.
  • 11
    Wong R, Lopaschuk G, Zhu G et al. Skeletal muscle metabolism in the chronic fatigue syndrome. In vivo assessment by 31P nuclear magnetic resonance spectroscopy. Chest 1992; 102: 171622.
  • 12
    McCully KK, Natelson BH, Iotti S, Sisto S, Leigh JS Jr. Reduced oxidative muscle metabolism in chronic fatigue syndrome. Muscle Nerve 1996; 19: 6215.
  • 13
    Fulcher KY, White PD. Strength and physiological response to exercise in patients with chronic fatigue syndrome. J Neurol Neurosurg Psychiatry 2000; 69: 3027.
  • 14
    Barnes PR, Taylor DJ, Kemp GJ, Radda GK. Skeletal muscle bioenergetics in chronic fatigue syndrome. J Neurol Neurosurg Psychiatry 1993; 56: 67983.
  • 15
    Imbar O, Dlin R, Rotstein A, Whipp BJ. Physiological responses to incremental exercise in patients with chronic fatigue syndrome. Med Sci Sports Exerc 2001; 33: 146370.
  • 16
    McCully KK, Smith S, Rajaei S, Leigh JS Jr, Natelson BH. Blood flow and muscle metabolism in chronic fatigue syndrome Clin Sci 2003; 104: 6417.
  • 17
    Mullis R, Campbell IT, Wearden AJ, Morriss RK, Pearson DJ. Prediction of peak oxygen uptake in chronic fatigue syndrome. Br J Sports Med 1999; 33: 3526.
  • 18
    Sargent C, Scroop GC, Nemeth PM, Burnet RB, Buckley JD. Maximal oxygen uptake and lactate metabolism are normal in chronic fatigue syndrome. Med Sci Sports Med 2002; 34: 516.
  • 19
    Sisto SA, LaManca J, Cordero DL et al. Metabolic and cardiovascular effects of a progressive exercise test in patients with chronic fatigue syndrome. Am J Med 1996; 100: 63440.
  • 20
    Lane RJ, Barrett MC, Taylor DJ, Kemp GJ, Lodi R. Heterogeneity in chronic fatigue syndrome: evidence from magnetic resonance spectroscopy of muscle. Neuromuscul Disord 1998; 8: 2049.
  • 21
    Lane RJ, Barrett MC, Woodrow D, Moss J, Fletcher R, Archard LC. Muscle fibre characteristics and lactate responses to exercise in chronic fatigue syndrome. J Neurol Neurosurg Psychiatry 1998; 64: 3627.
  • 22
    Murphy ME, Kehrer JP. Oxidative stress and muscular dystrophy. Chem Biol Interact 1989; 69: 10173.
  • 23
    Fulle S, Mecocci P, Fano G et al. Specific oxidative alterations in vastus lateralis muscle of patients with the diagnosis of chronic fatigue syndrome. Free Radic Biol Med 2000; 29: 12529.
  • 24
    Keenoy MY, Moorkens G, Vertommen J, De Leeuw I. Antioxidant status and lipoprotein peroxidation in chronic fatigue syndrome. Life Sci 2001; 68: 203749.
  • 25
    Richards RS, Roberts TK, McGregor NR, Dunstan RH, Butt HL. Blood parameters indicative of oxidative stress are associated with symptom expression in chronic fatigue syndrome. Redox Rep 2000; 5: 3541.
  • 26
    Vecchiet J, Cipollone F, Falasca K et al. Relationship between musculoskeletal symptoms and blood markers of oxidative stress in patients with chronic fatigue syndrome. Neurosci Lett 2003; 335: 1514.
  • 27
    Peterson PK, Sirr SA, Grammith FC et al. Effects of mild exercise on cytokines and cerebral blood flow in chronic fatigue syndrome. Clin Diagn Lab Immunol 1994; 1: 2226.
  • 28
    Cannon JG, Angel JB, Ball RW, Abad LW, Fagioli L, Komaroff AL. Acute phase responses and cytokine secretion in chronic fatigue syndrome. J Clin Immunol 1999; 19: 41421.
  • 29
    Arnaud S, Zattara-Hartmann MC, Tomei C, Jammes Y. Correlation between muscle metabolism and changes in M-wave and surface electromyogram: dynamic constant load leg exercise in untrained subjects. Muscle Nerve 1997; 20: 11979.
  • 30
    Jammes Y, Zattara-Hartmann MC, Caquelard F, Arnaud S, Tomei C. Electromyographic changes in vastus lateralis during dynamic exercise. Muscle Nerve 1997; 20: 2479.
  • 31
    Jammes Y, Steinberg JG, Bregeon F, Delliaux S. The oxidative stress in response to routine incremental cycling exercise in healthy sedentary subjects. Respir Physiol Neurobiol 2004; 144: 8190.
  • 32
    Davis JA, Frank MH, Whipp BJ, Wasserman K. Anaerobic threshold alterations caused by endurance training in middle-aged men. J Appl Physiol 1979; 46: 103946.
  • 33
    Uchiyama M, Mihara M. Determination of malonedialdehyde precursor in tissues by thiobarbituric acid test. Anal Biochem 1978; 86: 2718.
  • 34
    Yoshida T. Determination of reduced and oxidized glutathione in erythrocytes by high-performance liquid chromatography with ultraviolet absorbance detection. J Chromatogr B 1996; 678: 15764.
  • 35
    Maickel RP. A rapid procedure for the determination of adrenal ascorbic acid. Application of the Sullivan and Clarke method to tissues. Anal Biochem 1960; 1: 498501.
  • 36
    Plioplys AV, Plioplys S. Electron-microscopic investigation of muscle mitochondria in chronic fatigue syndrome. Neuropsychobiology 1995; 32: 17581.
  • 37
    Sen CK. Oxidants and antioxidants in exercise. J Appl Physiol 1995; 79: 67586.
  • 38
    Frei B, England L, Ames B. Ascorbate is an outstanding antioxidant in human blood plasma. Proc Natl Acad Sci USA 1989; 86: 637781.
  • 39
    Glascott PA Jr, Tsyganskaya M, Gilfor E, Zern MA, Farber JL. The antioxidant function of the physiological content of vitamin. Clin Mol Pharmacol 1996; 50: 9949.
  • 40
    Singh A, Garg V, Gupta S, Kulkarni SK. Role of antioxidants in chronic fatigue syndrome. Indian J Exp Biol 2002; 40: 12404.
  • 41
    Stuart G, Cadenas S, Jekabsons MD, Roussel D, Brand MD. Mitochondrial proton leak and the uncoupling protein 1 homologues. Biochem Biophys Acta 2001; 150: 14458.
  • 42
    Echtay KS, Roussel D, St-Pierre J et al. Superoxide activates mitochondrial uncoupling proteins. Nature 2002; 415: 969.
  • 43
    Bigland-Ritchie B, Kukulka CJ, Lippold OCJ, Woods JJ. The absence of neuromuscular transmission failure in sustained maximal voluntary contractions. J Physiol 1982; 330: 26578.
  • 44
    Marcos E, Ribas J. Kinetics of plasma potassium concentrations during exhausting exercise in trained and untrained men. Eur J Appl Physiol 1995; 71: 20714.