You have full text access to this OnlineOpen article
Abnormalities in pH handling by peripheral muscle and potential regulation by the autonomic nervous system in chronic fatigue syndrome
Article first published online: 20 AUG 2009
DOI: 10.1111/j.1365-2796.2009.02160.x
© 2010 Blackwell Publishing Ltd
Additional Information
How to Cite
Jones, D. E. J., Hollingsworth, K. G., Taylor, R., Blamire, A. M. and Newton, J. L. (2010), Abnormalities in pH handling by peripheral muscle and potential regulation by the autonomic nervous system in chronic fatigue syndrome. Journal of Internal Medicine, 267: 394–401. doi: 10.1111/j.1365-2796.2009.02160.x
Publication History
- Issue published online: 11 MAR 2010
- Article first published online: 20 AUG 2009
References
- 1Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (encephalopathy); diagnosis and management. http://www.nice.gov.org
- 2, . Neurally mediated hypotension and chronic fatigue syndrome. Am J Med 1998; 105: 15S–21S.
- 3, . The importance of orthostatic intolerance in the chronic fatigue syndrome. Am J Med Sci 1999; 317: 117–23.
- 4, , , . Orthostatic intolerance in the chronic fatigue syndrome. J Auton Nerv Syst 1999; 75: 192–201.
- 5, , , , , . Autonomic function and serum erythropoietin levels in chronic fatigue syndrome. J Psychosom Res 2004; 56: 179–83.
- 6, , , , , . Symptoms of autonomic dysfunction in chronic fatigue syndrome. QJM 2007; 100: 519–26.
- 7, . Does the chronic fatigue syndrome involve the autonomic nervous system? Am J Med 1997; 102: 357–64.
- 8, , et al. The postural orthostatic tachycardia syndrome: a potentially treatable cause of chronic fatigue, exercise intolerance, and cognitive impairment in adolescents. PACE 2000; 23: 344–51.
- 9, , et al. Cardiovascular response during head-up tilt in chronic fatigue syndrome. Clin Physiol 1999; 19: 111–20.
- 10, , , , , . Autonomic testing in patients with chronic fatigue syndrome. Am J Med 1998; 105: 22S–6S.
- 11, , , , . Use of time-frequency analysis to investigate temporal patterns of cardiac autonomic response during head-up tilt in chronic fatigue syndrome. Auton Neurosci 2004; 113: 55–62.
- 12, , . A measure of heart rate variability is sensitive to orthostatic challenge in women with chronic fatigue syndrome. Exp Biol Med 2003; 228: 167–74.
- 13, . Chronic fatigue syndrome: a hypothesis focusing on the autonomic nervous system. Clin Sci 1999; 96: 117–25.
- 14, , et al. Neurally mediated hypotension and autonomic dysfunction measured by heart rate variability during head-up tilt testing in children with chronic fatigue syndrome. Clin Autonom Res 1998; 8: 221–30.
- 15, , , , , . Hemodynamic and neurohumoral responses to head-up tilt in patients with chronic fatigue syndrome. Clin Auton Res 2002; 12: 273–80.
- 16, , et al. Abnormal impedance cardiography predicts symptom severity in chronic fatigue syndrome. Am J Med Sci 2003; 326: 55–60.
- 17. Autonomic nervous system dysfunction in adolescents with postural orthostatic tachycardia syndrome and chronic fatigue syndrome is characterized by attenuated vagal baroreflex and potentiated sympathetic vasomotion. Pediatr Res 2000; 48: 218–26.
- 18, . Locomotor muscle fatigue modifies central motor drive in healthy humans and imposes limitation to exercise performance. J Physiol 2008; 586: 161–73.
- 19, , et al. Pilot study of peripheral muscle function in primary biliary cirrhosis: potential implications for fatigue pathogenesis. CGH 2008; 6: 1041–8.
- 20, , , . Demonstration of delayed recovery from fatiguing exercise in chronic fatigue syndrome. Eur J Neurol 1999; 6: 63–9.
- 21. Muscle pH regulation: role of training. Acta Physiol Scand 1998; 162: 359–66.
- 22, . Evidence of extracellular mechanism for the action of H+ on recovery of muscles following fatigue. Can J Physiol Pharmacol 1982; 60: 1720–4.
- 23, , et al. The chronic fatigue syndrome: a comprehensive approach to its definition and study. Ann Intern Med 1994; 121: 953–9.
- 24, , . Definition and prevalence of sedentarism in an urban population. Am J Public Health 1999; 89: 862–7.
- 25, , , , , . Measuring the functional impact of fatigue: initial validation of the fatigue impact scale. Clin Infect Dis 1994; 18(Suppl 1): S79–83.
- 26, , , , . A rapid screening tool for fatigue impact in multiple sclerosis. BMC Neurol 2006; 6: 27.
- 27. ATP production rates as a function of force level in the human gastrocnemius/soleus using 31P MRS. Magn Res Med 1994; 32: 1–10.
- 28, , Improved method for accurate and efficient quantification of MRS data with use of prior knowledge. J Magn Reson 1997; 129: 35–43.
- 29, . Quantitative interpretation of bioenergetic data from 31P and 1H magnetic resonance spectroscopic muscle: an analytical review. Magn Reson Quart 1994; 10: 43–63.
- 30Anonymous. Heart rate variability: standards of measurement, physiological interpretation and clinical use. Task force of the European society of cardiology and the North American society of pacing and electrophysiology. Circulation 1996; 93: 1043–65.
- 31, , , . Proton efflux in human skeletal muscle during recovery from exercise. Eur J Appl Physiol 1997; 76: 462–71.
- 32, , et al. Mitochondrial function and oxygen supply in normal and chronically ischaemic muscle: a combined 31P magnetic resonance spectroscopy and near infrared spectroscopy study in vivo. J Vasc Surg 2001; 34: 1103–10.
- 33, , , , . The effect of beta 2-adrenoceptor stimulation and blockade of L-type calcium channels on in vivo Na+/H+ antiporter activity in rat skeletal muscle. Biochim Biophys Acta 1991; 1093: 234–40.
- 34, , , , . Heterogeneity in chronic fatigue syndrome: evidence from magnetic resonance spectroscopy of muscle. Neuro Disord 1998; 8: 204–9.
- 35, , et al. Skeletal muscle metabolism in the chronic fatigue syndrome. Chest 1992; 102: 1716–22.
- 36, , , , . Blood flow and muscle metabolism in the chronic fatigue syndrome. Clin Sci (Lond) 2003; 104: 641–7.
- 37, , , . Skeletal muscle bioenergetics in the chronic fatigue syndrome. JNNP 1993; 56: 679–83.
- 38, , . Chronic fatigue syndrome: an approach combining self-management with graded exercise to avoid exacerbations. J Rehab Med 2008; 40: 241–7.

1365-2796/asset/olbannerleft.gif?v=1&s=2c0da92fd7dd29d6387a79c865c2e722951f9b9b)
1365-2796/asset/olbannercenter.gif?v=1&s=e1b4b2f8709bbf2cd315f2b365ae538cedfe9fdf)
1365-2796/asset/olbannerright.gif?v=1&s=99fa1da70758a077581e13cbfc3cd514826924d8)
