Figure S1. B cell phenotype during HIV-1 infection.

Figure S2. Plasma IL-21 levels are decreased during HIV-1 infection.

Figure S3. Percentages of CD38 expression in total, naïve, classical (CD27+) memory, resting memory (RM’), activated memory (AM) and tissue-like memory (TLM) B cells were correlated with CD4 T cell counts (A and B) and HIV-1 viraemia (C) measured in total HIV-1-infected patients (n = 40, A) and patients naïve to treatment (n = 20, B and C).

Figure S4. Plasma levels of LPS are correlated with IL-21R in RM B cells.

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