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  • Bachofen, H., Ammann, A., Wangensteen, D. and Weibel, E.R. (1982) Perfusion fixation of lungs for structure-function analysis: credits and limitations. J. Appl. Physiol. 53, 528533.
  • Baddeley, A.J., Gundersen, H.J.G. and Cruz-Orive, L.M. (1986) Estimation of surface area from vertical sections. J. Microsc. 142, 259276.
  • Baddeley, A. and Vedel Jensen, E.B. (2005) Stereology for Statisticians. Chapman and Hall, Boca Raton.
  • Baumeister, W. (2002) Electron tomography: towards visualizing the molecular organization of the cytoplasm. Curr. Opin. Struct. Biol. 12, 679684.
  • Bendayan, M. (2001) Worth its weight in gold. Science, 291, 13631365.
  • Bolender, R.P., Hyde, D.M. and DeHoff, R.T. (1993) Lung morphometry: a new generation of tools and experiments for organ, tissue, cell, and molecular biology. Am. J. Physiol. Lung Cell. Mol. Physiol. 265, L521L548.
  • Bonetta, L. (2005) Zooming in on electron tomography. Nat. Meth, 2, 139145.
  • Braendgaard, H. and Gundersen, H.J.G. (1986) The impact of recent stereological advances on quantitative studies of the nervous system. J. Neurosci. Meth. 18, 3978.
  • Brasch, F., Johnen, G., Winn-Brasch, A., Guttentag, S.H., Schmiedl, A., Kapp, N., Suzuki, Y., Müller, K.M., Richter, J., Hawgood, S. and Ochs, M. (2004) Surfactant protein B in type II pneumocytes and intra-alveolar surfactant forms of human lungs. Am. J. Respir. Cell Mol. Biol. 30, 449458.
  • Casley-Smith, J.R. (1988) Expressing stereological results ‘per cm3’ is not enough. J. Pathol. 156, 263265.
  • Clements, J.A. (1997) Lung surfactant: a personal perspective. Annu. Rev. Physiol. 59, 121.
  • Coggeshall, R.E. and Lekan, H.A. (1996) Methods for determining numbers of cells and synapses: a case for more uniform standards of review. J. Comp. Neurol. 364, 615.
  • Crouch, E. and Wright, J.R. (2001) Surfactant proteins A and D and pulmonary host defense. Annu. Rev. Physiol. 63, 521554.
  • Cruz-Orive, L.M. (1987) Particle number can be estimated using a disector of unknown thickness: the selector. J. Microsc. 145, 121142.
  • Cruz-Orive, L.M. (1997) Stereology of single objects. J. Microsc. 186, 93107.
  • Cruz-Orive, L.M. and Weibel, E.R. (1981) Sampling designs for stereology. J. Microsc. 122, 235257.
  • Cruz-Orive, L.M. and Weibel, E.R. (1990) Recent stereological methods for cell biology: a brief survey. Am. J. Physiol. Lung Cell. Mol. Physiol. 258, L148L156.
  • Dorph-Petersen, K.A., Nyengaard, J.R. and Gundersen, H.J.G. (2001) Tissue shrinkage and unbiased stereological estimation of particle number and size. J. Microsc. 204, 232246.
  • Elias, H. (1972) Identification of structure by the common-sense approach. J. Microsc. 95, 5968.
  • Fehrenbach, H. (2001) Alveolar epithelial type II cell: defender of the alveolus revisited. Respir. Res. 2, 3346.
  • Fehrenbach, H. (200203) Animal models of chronic obstructive pulmonary disease: some critical remarks. Pathobiology, 70, 277283.
  • Fehrenbach, A., Fehrenbach, H., Wittwer, T., Ochs, M., Wahlers, T. and Richter, J. (2001) Evaluation of pulmonary edema: stereological versus gravimetrical analysis. Eur. Surg. Res. 33, 270278.
  • Fehrenbach, H. and Ochs, M. (1998) Studying lung ultrastructure. In: Uhlig, S. and Taylor, A.E., eds. Methods in Pulmonary Research, pp. 429454. Birkhäuser, Basel.
  • Fehrenbach, A., Ochs, M., Warnecke, T., Wahlers, T., Wittwer, T., Schmiedl, A., Elki, S., Meyer, D., Richter, J. and Fehrenbach, H. (2000) Beneficial effect of lung preservation is related to ultrastructural integrity of tubular myelin after experimental ischemia and reperfusion. Am. J. Respir. Crit. Care Med. 161, 20582065.
  • Fehrenbach, A., Ochs, M., Wittwer, T., Cornelius, J., Fehrenbach, H., Wahlers, T. and Richter, J. (1999) Stereological estimation of the Volume weighted mean Volumes of alveoli and acinar pathways in the rat lung to characterise alterations after ischaemia/reperfusion. J. Anat. 194, 127135.
  • Gehr, P., Bachofen, M. and Weibel, E.R. (1978) The normal human lung: ultrastructure and morphometric estimation of diffusion capacity. Respir. Physiol. 32, 121140.
  • Geiser, M., Cruz-Orive, L.M., Im Hof, V. and Gehr, P. (1990) Assessment of particle retention and clearance in the intrapulmonary conducting airways of hamster lungs with the fractionator. J. Microsc. 160, 7588.
  • Gerrits, P.O. and Horobin, R.W. (1996) Glycol methacrylate embedding for light microscopy: basic principles and trouble-shooting. J. Histotechnol. 19, 297311.
  • Gil, J. (1990) Controlled and reproducible fixation of the lung for correlated studies. In: Gil, J., ed. Models of Lung Disease. Lung Biology in Health and Disease, Vol. 47. Marcel Dekker, New York, 322.
  • Griffiths, G. (1993) Fine Structure Immunocytochemistry. Springer, Berlin.
  • Griffiths, G. (2001) Bringing electron microscopy back into focus for cell biology. Trends Cell Biol. 11, 153154.
  • Griffiths, G., Parton, R.G., Lucocq, J., Van Deurs, B., Brown, D., Slot, J.W. and Geuze, H.J. (1993) The immunofluorescent era of membrane traffic. Trends Cell Biol. 3, 214219.
  • Gundersen, H.J.G. (1977) Notes on the estimation of the numerical density of arbitrary profiles: the edge effect. J. Microsc. 111, 219223.
  • Gundersen, H.J.G. (1986) Stereology of arbitrary particles. A review of unbiased number and size estimators and the presentation of some new ones, in memory of William R. Thompson. J. Microsc. 143, 345.
  • Gundersen, H.J.G. (1988) The nucleator. J. Microsc. 151, 321.
  • Gundersen, H.J.G. (2002) The smooth fractionator. J. Microsc. 207, 191210.
  • Gundersen, H.J.G., Bagger, P., Bendtsen, T.F., Evans, S.M., Korbo, L., Marcussen, N., Møller, A., Nielsen, K., Nyengaard, J.R., Pakkenberg, B., Sørensen, F.B., Vesterby, A. and West, M.J. (1988b) The new stereological tools: Disector, fractionator, nucleator and point sampled intercepts and their use in pathological research and diagnosis. APMIS, 96, 857881.
  • Gundersen, H.J.G., Bendtsen, T.F., Korbo, L., Marcussen, N., Møller, A., Nielsen, K., Nyengaard, J.R., Pakkenberg, B., Sørensen, F.B., Vesterby, A. and West, M.J. (1988a) Some new, simple and efficient stereological methods and their use in pathological research and diagnosis. APMIS, 96, 379394.
  • Gundersen, H.J.G., Boyce, R.W., Nyengaard, J.R. and Odgaard, A. (1993) The conneulor: unbiased estimation of connectivity using physical disectors under projection. Bone, 14, 217222.
  • Gundersen, H.J.G. and Jensen, E.B. (1985) Stereological estimation of the volume-weighted mean Volume of arbitrary particles observed on random sections. J. Microsc. 138, 127142.
  • Gundersen, H.J.G. and Jensen, E.B. (1987) The efficiency of systematic sampling in stereology and its prediction. J. Microsc. 147, 229263.
  • Gundersen, H.J.G. and Østerby, R. (1981) Optimizing sampling efficiency of stereological studies in biology: or ‘Do more less well!’. J. Microsc. 121, 6573.
  • Hawgood, S. (1997) Surfactant: composition, structure, and metabolism. In: Crystal, R.G., West, J.B., Weibel, E.R. and Barnes, P.J., eds. The Lung. Scientific Foundations, 2nd edn. pp. 557571, Lippincott-Raven, Philadelphia.
  • Hawgood, S., Ochs, M., Jung, A., Akiyama, J., Allen, L., Brown, C., Edmondson, J., Levitt, S., Carlson, E., Gillespie, A.M., Villar, A., Epstein, C.J. and Poulain, F.R. (2002) Sequential targeted deficiency of SP-A and -D leads to progressive alveolar lipoproteinosis and emphysema. Am. J. Physiol. Lung Cell. Mol. Physiol. 283, L1002L1010.
  • Hawgood, S. and Poulain, F.R. (2001) The pulmonary collectins and surfactant metabolism. Annu. Rev. Physiol. 63, 495519.
  • Hayat, M.A. (2000) Principles and techniques of electron microscopy. Biological Applications, 4th edn. Cambridge University Press, Cambridge.
  • Heemskerk-Gerritsen, B.A., Dijkman, J.H. and Ten Have-Opbroek, A.A. (1996) Stereological methods: a new approach in the assessment of pulmonary emphysema. Microsc. Res. Techn, 34, 556562.
  • Howard, C.V. and Reed, M.G. (2005) Unbiased stereology. Three-Dimensional Measurement in Microscopy, 2nd edn. Bios, Oxford.
  • Hyde, D.M., Tyler, N.K., Putney, L.F., Singh, P. and Gundersen, H.J.G. (2004) Total number and mean size of alveoli in mammalian lung estimated using fractionator sampling and unbiased estimates of the Euler characteristic of alveolar openings. Anat. Rec. 277, 216226.
  • Jung, A., Allen, L., Nyengaard, J.R., Gundersen, H.J.G., Richter, J., Hawgood, S. and Ochs, M. (2005) Design-based stereological analysis of the lung parenchymal architecture and alveolar type II cells in surfactant protein A and D double deficient mice. Anat. Rec. 286, 885890.
  • Keller, H. and Eggli, P. (1998) Actin accumulation in pseudopods or in the tail of polarized Walker carcinosarcoma cells quantitatively correlates with local folding of the cell surface membrane. Cell Motil. Cytoskeleton, 40, 342353.
  • Kordower, J.H. (2000) Making the counts count: the stereology revolution. J. Chem. Neuroanat. 20, 12.
  • Koster, A.J. and Klumperman, J. (2003) Electron microscopy in cell biology: integrating structure and function. Nat. Rev. Mol. Cell Biol. September (Suppl.), SS6SS10.
  • Kroustrup, J.P. and Gundersen, H.J.G. (1983) Sampling problems in an heterogeneous organ: quantitation of relative and total Volume of pancreatic islets by light microscopy. J. Microsc. 132, 4355.
  • Kroustrup, J.P. and Gundersen, H.J.G. (2001) Estimating the number of complex particles using the ConnEulor principle. J. Microsc. 203, 314320.
  • Kubinova, L. and Janacek, J. (2001) Confocal microscopy and stereology: estimating volume, number, surface area and length by virtual test probes applied to three-dimensional images. Microsc. Res. Techn, 53, 425435.
  • Lewis, J.F., Novick, R.J. and Veldhuizen, R.A.W. (1997) Surfactant in Lung Injury and Lung Transplantation. New York: Springer.
  • Lucocq, J.M. (1994) Quantitation of gold labelling and antigens in immunolabelled ultrathin sections. J. Anat. 184, 113.
  • Lucocq, J.M., Habermann, A., Watt, S., Backer, J.M., Mayhew, T.M. and Griffiths, G. (2004) A rapid method for assessing the distribution of gold labeling on thin sections. J. Histochem. Cytochem. 52, 9911000.
  • Madsen, K.M. (1999) The art of counting. J. Am. Soc. Nephrol. 10, 11241125.
  • Mason, R.J. and Shannon, J.M. (1997) Alveolar type II cells. In: Crystal, R.G., West, J.B., Weibel, E.R. and Barnes, P.J., eds. The Lung. Scientific Foundations, 2nd edn. pp. 543555, Lippincott-Raven, Philadelphia.
  • Massaro, G.D. and Massaro, D. (1996) Formation of pulmonary alveoli and gas-exchange surface area: quantitation and regulation. Annu. Rev. Physiol. 58, 7392.
  • Massaro, G.D.C., Radaeva, S., Clerch, L.B. and Massaro, D. (2002) Lung alveoli: endogenous programmed destruction and regeneration. Am. J. Physiol. Lung Cell. Mol. Physiol. 283, L305L309.
  • Mattfeldt, T., Mall, G., Gharehbaghi, H. and Möller, P. (1990) Estimation of surface area and length with the orientator. J. Microsc. 159, 301317.
  • Mayhew, T.M. (1991) The new stereological methods for interpreting functional morphology from slices of cells and organs. Exp. Physiol. 76, 639665.
  • Mayhew, T.M., Griffiths, G., Habermann, A., Lucocq, J., Emre, N. and Webster, P. (2003) A simpler way of comparing the labelling densities of cellular compartments illustrated using data from VPARP and LAMP-1 immunogold labelling experiments. Histochem. Cell Biol. 119, 333341.
  • Mayhew, T.M., Griffiths, G. and Lucocq, J.M. (2004) Applications of an efficient method for comparing immunogold labelling patterns in the same set of compartments in different groups of cells. Histochem. Cell Biol. 122, 171177.
  • Mayhew, T.M. and Gundersen, H.J.G. (1996) ‘If you assume, you can make an ass out of u and me’: a decade of the disector for stereological counting of particles in 3D space. J. Anat. 188, 115.
  • Mayhew, T.M., Luqocq, J.M. and Griffiths, G. (2002) Relative labelling index: a novel stereological approach to test for non-random immunogold labelling of organelles and membranes on transmission electron microscopy thin sections. J. Microsc. 205, 153164.
  • McCormack, F.X. and Whitsett, J.A. (2002) The pulmonary collectins, SP-A and SP-D, orchestrate innate immunity in the lung. J. Clin. Invest. 109, 707712.
  • McIntosh, J.R. (2001) Electron microscopy of cells: a new beginning for a new century. J. Cell Biol. 153, F25F32.
  • McIntosh, R., Nicastro, D. and Mastronarde, D. (2005) New views of cells in 3D: an introduction to electron tomography. Trends Cell Biol. 15, 4351.
  • Michel, R.P. and Cruz-Orive, L.M. (1988) Application of the Cavalieri principle and vertical sections method to lung: estimation of Volume and pleural surface area. J. Microsc. 150, 117136.
  • Notter, R.H. (2000) Lung surfactants. Basic science and clinical applications. Lung Biology in Health and Disease, Vol. 149. Marcel Dekker, New York.
  • Nyengaard, J.R. (1999) Stereologic methods and their application in kidney research. J. Am. Soc. Nephrol. 10, 11001123.
  • Nyengaard, J.R. and Gundersen, H.J.G. (1992) The isector: a simple and direct method for generating isotropic, uniform random sections from small specimens. J. Microsc. 165, 427431.
  • Nyengaard, J.R. and Marcussen, N. (1993) The number of glomerular capillaries estimated by an unbiased and efficient stereological method. J. Microsc. 171, 2737.
  • Ochs, M. (2001) Pulmonary surfactant preservation in experimental and clinical lung transplantation. In: Pandalai, S.G., ed. Recent Research Developments in Respiratory and Critical Care Medicine. Research Signpost, Trivandrum, 5981.
  • Ochs, M., Fehrenbach, H., Nenadic, I., Bando, T., Fehrenbach, A., Schepelmann, D., Albes, J.M., Wahlers, T. and Richter, J. (2000) Preservation of intraalveolar surfactant in a rat lung ischaemia/reperfusion injury model. Eur. Respir. J. 15, 526531.
  • Ochs, M., Johnen, G., Müller, K.M., Wahlers, T., Hawgood, S., Richter, J. and Brasch, F. (2002) Intracellular and intraalveolar localization of surfactant protein A (SP-A) in the parenchymal region of the human lung. Am. J. Respir. Cell Mol. Biol. 26, 9198.
  • Ochs, M., Knudsen, L., Allen, L., Stumbaugh, A., Levitt, S., Nyengaard, J.R. and Hawgood, S. (2004a) GM-CSF mediates alveolar epithelial type II cell changes but not emphysema-like pathology in SP-D deficient mice. Am. J. Physiol. Lung Cell. Mol. Physiol. 287, L1333L1341.
  • Ochs, M., Nenadic, I., Fehrenbach, A., Albes, J.M., Wahlers, T., Richter, J. and Fehrenbach, H. (1999) Ultrastructural alterations in intraalveolar surfactant subtypes after experimental ischemia and reperfusion. Am. J. Respir. Crit. Care Med. 160, 718724.
  • Ochs, M., Nyengaard, J.R., Jung, A., Knudsen, L., Voigt, M., Wahlers, T., Richter, J. and Gundersen, H.J.G. (2004b) The number of alveoli in the human lung. Am. J. Respir. Crit. Care Med. 169, 120124.
  • Ochs, M., Nyengaard, J.R., Waizy, H., Wahlers, T., Gundersen, H.J.G. and Richter, J. (2001) Alveolar type II cells and the intracellular surfactant pool in the human lung – a stereological approach. Am. J. Respir. Crit. Care Med. 163, A731. (Abstract).
  • Ogbuihi, S. and Cruz-Orive, L.M. (1990) Estimating the total number of lymphatic valves in infant lungs with the fractionator. J. Microsc. 158, 1930.
  • Oldmixon, E.H., Suzuki, S., Butler, J.P. and Hoppin, F.G. Jr (1985) Perfusion dehydration fixes elastin and preserves lung air-space dimensions. J. Appl. Physiol. 58, 105113.
  • Pache, J.C., Roberts, N., Vock, P., Zimmermann, A. and Cruz-Orive, L.M. (1993) Vertical LM sectioning and parallel CT scanning designs for stereology: application to human lung. J. Microsc. 170, 924.
  • Recheis, W., McLennan, G., Ross, A.F., Hoffman, E.A., Clough, A.V. and Haworth, S.T. (2005) Imaging the mouse lung with micro-CT. In: Schuster, D.P. and Blackwell, T.S., eds. Molecular Imaging of the Lungs. Lung Biology in Health and Disease, Vol. 203. pp. 135169 Taylor and Francis, Boca Raton.
  • Roberts, N., Puddephat, M.J. and McNulty, V. (2000) The benefit of stereology for quantitative radiology. Br. J. Radiol. 73, 679697.
  • Scherle, W. (1970) A simple method for volumetry of organs in quantitative stereology. Mikroskopie, 26, 5760.
  • Schmiedl, A., Ochs, M., Mühlfeld, C., Johnen, G. and Brasch, F. (2005) Distribution of surfactant proteins in type II pneumocytes of newborn, 14-day old, and adult rats: an immunoelectron microscopic and stereological study. Histochem. Cell Biol. 124, 465476.
  • Skepper, J.N. (2000) Immunocytochemical strategies for electron microscopy: choice or compromise. J. Microsc. 199, 136.
  • Sterio, D.C. (1984) The unbiased estimation of number and sizes of arbitrary particles using the disector. J. Microsc. 134, 127136.
  • Studer, D., Graber, W., Al-Amoudi, A. and Eggli, P. (2001) A new approach for cryofixation by high-pressure freezing. J. Microsc. 203, 285294.
  • Thomsen, J.S., Laib, A., Koller, B., Prohaska, S., Mosekilde, L.I. and Gowin, W. (2005) Stereological measures of trabecular bone structure: comparison of 3D micro computed tomography with 2D histological sections in human proximal tibial bone biopsies. J. Microsc. 218, 171179.
  • Vanhecke, D., Graber, W., Herrmann, G., Al-Amoudi, A., Eggli, P. and Studer, D. (2003) A rapid microbiopsy system to improve the preservation of biological samples prior to high-pressure freezing. J. Microsc. 212, 312.
  • Vedel Jensen, E.B. and Gundersen, H.J.G. (1993) The rotator. J. Microsc. 170, 3544.
  • Waizy, H., Fehrenbach, H., Wahlers, T., Richter, J. and Ochs, M. (2001) Alterations in intracellular surfactant of the rat lung in response to ischemia-reperfusion injury. Am. J. Respir. Crit. Care Med. 163, A732. (Abstract).
  • Wangensteen, D., Bachofen, H. and Weibel, E.R. (1981) Effects of glutaraldehyde or osmium tetroxide fixation on the osmotic properties of lung cells. J. Microsc. 124, 189196.
  • Weibel, E.R. (1963) Morphometry of the Human Lung. Springer, Berlin.
  • Weibel, E.R. (1979) Stereological Methods, Vol. 1: Practical Methods for Biological Morphometry. Academic Press, London.
  • Weibel, E.R. (1980) Stereological Methods, Vol. 2: Theoretical Foundations. Academic Press, London.
  • Weibel, E.R. (1981) Stereological methods in cell biology: where are we – where are we going? J. Histochem. Cytochem. 29, 10431052.
  • Weibel, E.R. (1984a) The Pathway for Oxygen. Harvard University Press, Cambridge, MA.
  • Weibel, E.R. (1984b) Morphometric and stereological methods in respiratory physiology, including fixation techniques. In: Otis, A.B., ed. Techniques in the Life Sciences. Techniques in Respiratory Physiology, Part 1. pp. 135, Elsevier, County Clare.
  • Weibel, E.R. (1996) The structural basis of lung function. In: West, J.B., ed. Respiratory Physiology. People and Ideas. pp. 346, Oxford University Press, New York.
  • Weibel, E.R. (2001) Why measure lung structure? Am. J. Respir. Crit. Care Med. 163, 314315.
  • Weibel, E.R. and Cruz-Orive, L.M. (1997) Morphometric methods. In: Crystal, R.G., West, J.B., Weibel, E.R. and Barnes, P.J., eds. The Lung. Scientific Foundations, 2nd edn. pp. 333344, Lippincott-Raven, Philadelphia.
  • Weibel, E.R. and Gomez, D.M. (1962) A principle for counting tissue structures on random sections. J. Appl. Physiol. 17, 343348.
  • Weibel, E.R., Limacher, W. and Bachofen, H. (1982) Electron microscopy of rapidly frozen lungs: evaluation on the basis of standard criteria. J. Appl. Physiol. 53, 516527.
  • West, M.J. and Coleman, P.D. (1996) How to count. Neurobiol. Aging, 17, 503.
  • Whitsett, J.A. and Weaver, T.E. (2002) Hydrophobic surfactant proteins in lung function and disease. N. Engl. J. Med. 347, 21412148.
  • Wiebe, B.M. and Laursen, H. (1998) Lung morphometry by unbiased methods in emphysema: bronchial and blood vessel volume, alveolar surface area and capillary length. APMIS, 106, 651656.
  • Wright, J.R. (1997) Immunomodulatory functions of surfactant. Physiol. Rev. 77, 931962.
  • Wright, J.R. (2005) Immunoregulatory functions of surfactant proteins. Nat. Rev. Immunol. 5, 5868.
  • Yan, X., Polo Carbayo, J.J., Weibel, E.R. and Hsia, C.C.W. (2003) Variation of lung volume after fixation when measured by immersion or Cavalieri method. Am. J. Physiol. Lung Cell. Mol. Physiol. 284, L242L245.
  • Yang, Z.W., Qin, Y.H. and Su, S.R. (2002) Use of star volume to measure the size of the alveolar space in the asthmatic guinea-pig lung. Respirology, 7, 117121.