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Hypothalamic Control of the Pituitary-Gonadal Axis in Higher Primates: Key Advances over the Last Two Decades

  1. T. M. Plant

Article first published online: 10 JUL 2008

DOI: 10.1111/j.1365-2826.2008.01708.x

Issue

Journal of Neuroendocrinology

Journal of Neuroendocrinology

Special Issue: 20th Anniversary Special Issue 'From Molecular to Translational Neurobiology'

Volume 20, Issue 6, pages 719–726, June 2008

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How to Cite

Plant, T. M. (2008), Hypothalamic Control of the Pituitary-Gonadal Axis in Higher Primates: Key Advances over the Last Two Decades. Journal of Neuroendocrinology, 20: 719–726. doi: 10.1111/j.1365-2826.2008.01708.x

Author Information

  1. Department of Cell Biology and Physiology, University of Pittsburgh, Magee-Womens Research Institute, Pittsburgh, PA, USA.

*Tony M. Plant, Department of Cell Biology and Physiology, University of Pittsburgh, Magee-Womens Research Institute, 204 Craft Avenue; Rm. B311, Pittsburgh, PA 15213, USA (e-mail: plant1@pitt.edu).

Publication History

  1. Issue published online: 10 JUL 2008
  2. Article first published online: 10 JUL 2008
  3. Received: 29 February 2008, accepted 10 March 2008

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Keywords:

  • puberty;
  • ovulation;
  • primate;
  • GnRH;
  • kisspeptin

This review provides a brief historical background to the foundation of primate reproductive neuroendocrinology that was laid by Ernst Knobil during the late 1960s and early 1970s. This is followed by a discussion of studies conducted over the last two decades that I view as having contributed to the current understanding of the field of primate reproductive neuroendocrinology. The review concludes with a short summary of key questions that remain to be addressed.

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