Uncommon side-effects of interferon


INSERM U271, 157 Cours Albert Thomas, F-69424 Lyon Cedex 03, France.


Summary. Beside the clinical manifestations usually observed during the treatment of chronic viral hepatitis with interferon, a small number of side-effects, less frequent and sometimes unexpected, have been described. These neurological, pulmonary, metabolic, cardio-vascular or psychiatric manifestations are uncommon but potentially severe. We here describe three cases of stroke that occured during treatment with interferon in which the role played by the molecule could be questioned.