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Treatment of hepatitis C

Authors


Janice Main, Faculty of Medicine, Imperial College, St Mary's Hospital, Praed Street, London W2 1NY, UK.
E-mail: j.main@imperial.ac.uk

Abstract

Summary.  The combination of pegylated interferon alpha and ribavirin has improved treatment success rates in patients with hepatitis C with sustained response rates of just over 50% overall and more than 70% for those with genotypes 2 and 3. This article reviews the use of combination therapy, contraindications, factors influencing response and describes approaches to specific patient groups.

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