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Table S1 The 969 candidate genes that are differentially expressed between 2La and 2L+a karyotypes in response to heat hardening (38 °C, 1-hour).

Table S2 The 27 genes located inside the 2La rearrangement (in the AgamP3.6 gene set) that may function in the regulation of transcription according to their associated GO terms and/or the KEGG transcription factor database.

Fig. S1 Proteosome components from the KEGG/DAVID database. Boxes with green/white fill indicate genes with/without identified homologs in An.  gambiae. Genes differentially responsive to heat stress are outlined by green circles (up-regulated in 2La samples) or blue boxes (up-regulated in 2La and down-regulated in 2L+a). Corresponding An.  gambiae gene identifiers are shown adjacent to the candidate genes; only the numerical part of the gene ID is indicated, after omitting the leading letters (AGAP) and zeros.

Fig. S2 TCA cycle pathway from the KEGG/DAVID database. Boxes with green/white fill indicate genes with/without identified homologs in An.  gambiae. Genes differentially responsive to heat stress are outlined by green circles (up-regulated in 2La samples) or blue boxes (up-regulated in 2La and down-regulated in 2L+a). Enzyme names and corresponding An.  gambiae gene identifiers are shown adjacent to the candidate genes; only the numerical part of the gene ID is indicated, after omitting the leading letters (AGAP) and zeros.

Fig. S3 Glycolysis/gluconeogenesis pathway from the KEGG/DAVID database. Boxes with green/white fill indicate genes with/without identified homologs in An.  gambiae. Genes differentially responsive to heat stress are outlined by green circles (up-regulated in 2La samples) or blue boxes (up-regulated in 2La and down-regulated in 2L+a). Enzyme names and corresponding An. gambiae gene identifiers are shown adjacent to the candidate genes; only the numerical part of the gene ID is indicated, after omitting the leading letters (AGAP) and zeros.

Fig. S4 Oxidative phosphorylation pathway from the KEGG/DAVID database. Boxes with green/white fill indicate genes with/without identified homologs in An.  gambiae. Genes differentially responsive to heat stress are outlined by green circles (up-regulated in 2La samples), red circles (down-regulated in 2L+a) or blue boxes (up-regulated in 2La and down-regulated in 2L+a). Enzyme names and corresponding An.  gambiae gene identifiers are shown adjacent to the candidate genes; only the numerical part of the gene ID is indicated, after omitting the leading letters (AGAP) and zeros.

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MEC_5114_sm_Figures.pdf21775KSupporting info item
MEC_5114_sm_Table_S1.xls1120KSupporting info item
MEC_5114_sm_Table_S2.xls29KSupporting info item

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