Fig. S1 Experimental design and temperature curves of the experiment.

Fig. S2 Schematic diagrams for microarray experimental design.

Fig. S3 Venn diagrams for differential expression of genes distribution according to temperature (T), UVR and temperature + UVR (T/UVR) stress at 1, 2 and 5 days.

Fig. S4 Alignment of the Dermatopontin protein homologs. We started using human and Biomphalaria published Dermatopontin (DPT) protein sequences as bait.

Fig. S5 Genomic sequence of the N. vectensis jgi scaffold 152 (from 387969 to 426372) with deduced amino acids sequences corresponding to NvDPTa-d.

Table S1 List of all differentially expressed genes (|Fold|>1.3) identified in response to thermal and/or UVR stress.

Table S2 Gastrodermal and epidermal gene expression at 0, 12h and 36h in response to thermal and UVR stress.

Table S3 Uniseq cDNA sequences (ESTs assembling) used in the manuscript.

Table S4 Zooxanthellae density.

Table S5 RT-qPCR raw data.

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