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Table S1 Summary of seawater parameters in control and acidification treatments.

Table S2 Differentially expressed genes belonging to the GO category “extracellular region GO:0005576”.

Table S3 List of differentially expressed genes belonging to the GO category “mitochondrion GO:0005739”.

Table S4 The response of calcium transporters to elevated levels of CO2.

Table S5 The response of proton transporters to elevated levels of CO2.

Table S6 The response of bicarbonate transporters to elevated levels of CO2.

Table S7 The response of carbonic anhydrases to elevated levels of CO2.

Table S8 The response of skeletal organic matrix proteins to elevated levels of CO2.

Table S9 Primer sequences for the genes tested by real-time quantitative PCR.

Fig. S1 Fold-change distribution of the differentially expressed genes.

Fig. S2 Validation of the RNA-seq results by quantitative PCR.

Fig. S3 Quantitative comparison of expression profiles obtained from RNA-seq and RT-qPCR analysis.

Appendix S1 Supplementary methods.

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MEC_5554_sm_FigS1-S3_TableS1-S9.pdf1155KSupporting info item

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