Archaeal transcription and its regulators
Article first published online: 31 MAR 2005
Volume 56, Issue 6, pages 1397–1407, June 2005
How to Cite
Geiduschek, E. P. and Ouhammouch, M. (2005), Archaeal transcription and its regulators. Molecular Microbiology, 56: 1397–1407. doi: 10.1111/j.1365-2958.2005.04627.x
- Issue published online: 29 APR 2005
- Article first published online: 31 MAR 2005
- Accepted 18 February, 2005.
The relatively complex archaeal RNA polymerases are constructed along eukaryotic lines, and require two initiation factors for promoter recognition and specific transcription that are homologues of the RNA polymerase II TATA-binding protein and TFIIB. Many archaea also produce histones. In contrast, the transcriptional regulators encoded by archaeal genomes are primarily of bacterial rather than eukaryotic type. It is this combination of elements commonly regarded as separate and mutually exclusive that promises unifying insights into basic transcription mechanisms across all three domains of life.