The order of the ring: assembly of Escherichia coli cell division components
Article first published online: 1 JUN 2006
Volume 61, Issue 1, pages 5–8, July 2006
How to Cite
Vicente, M. and Rico, A. I. (2006), The order of the ring: assembly of Escherichia coli cell division components. Molecular Microbiology, 61: 5–8. doi: 10.1111/j.1365-2958.2006.05233.x
- Issue published online: 1 JUN 2006
- Article first published online: 1 JUN 2006
- Accepted 8 May, 2006.
Topological cues appear to override temporal events in the assembly of the Escherichia coli cell division ring. When a procedure that allows the recruitment of ring components based on their topological properties is used, a concerted mode of assembly of several components of the divisome, rather than a strict linear mode, is revealed. Three multimolecular complexes, the proto-ring, the periplasmic connector and the peptidoglycan factory, show some degree of concertation for their assembly. In addition, back-recruitment of all late proteins except FtsN into the division ring occurs even in the absence of proteins incorporated at earlier stages, i.e. FtsA or FtsQ.