SEARCH

SEARCH BY CITATION

References

  • Alderwick, L.J., Radmacher, E., Seidel, M., Gande, R., Hitcher, P.G., Morris, H.R., Dell, A., Sahm, H., Eggeling, L., and Besra, G.S. (2005) Deletion of Cg-emb in corynebacterianeae leads to a novel truncated cell wall arabinogalactan, whereas inactivation of Cg-ubiA results in an arabinan-deficient mutant with a cell wall galactan core. J Biol Chem 280: 3236232371.
  • Anderton, M.C., Bhakta, S., Besra, G.S., Jeavons, P., Eltis, L.D., and Sim, E. (2006) Characterization of the putative operon containing arylamine N-acetyltransferase (nat) in Mycobacterium bovis BCG. Mol Microbiol 59: 181192.
  • Ando, M., Yoshimatsu, T., Ko, C., Converse, P.J., and Bishai, W.R. (2003) Deletion of Mycobacterium tuberculosis sigma factor E results in delayed time to death with bacterial persistence in the lungs of aerosol-infected mice. Infect Immun 71: 71707172.
  • Arruda, S., Bomfim, G., Knights, R., Huima-Byron, T., and Riley, L.W. (1993) Cloning of an M. tuberculosis DNA fragment associated with entry and survival inside cells. Science 261: 14541457.
  • Bailey, T.L., and Elkan, C. (1994) Fitting a mixture model by expectation maximization to discover motifs in biopolymers. Proc Int Conf Intell Syst Mol Biol 2: 2836.
  • Bailey, T.L., and Gribskov, M. (1998) Combining evidence using p-values: application to sequence homology searches. Bioinformatics 14: 4854.
  • Baulard, A.R., Betts, J.C., Engohang-Ndong, J., Quan, S., McAdam, R.A., Brennan, P.J., et al. (2000) Activation of the pro-drug ethionamide is regulated in mycobacteria. J Biol Chem 275: 2832628331.
  • Benjamini, Y., and Hochberg, Y. (1995) Controlling false discovery rate: a practical and powerful approach to multiple testing. J Roy Stat Soc B 75: 289300.
  • Bhakta, S., Besra, G.S., Upton, A.M., Parish, T., Sholto-Douglas-Vernon, C., Gibson, K.J., et al. (2004) Arylamine N-acetyltransferase is required for synthesis of mycolic acids and complex lipids in Mycobacterium bovis BCG and represents a novel drug target. J Exp Med 199: 11911199.
  • Bishai, W. (2000) Lipid lunch for persistent pathogen. Nature 406: 683685.
  • Burguiere, A., Hitchen, P.G., Dover, L.G., Kremer, L., Ridell, M., Alexander, D.C., Liu, J., Morris, H.R., Minnikin, D.E., Dell, A., and Besra, G.S. (2005) LosA, a key glycosyltransferase involved in the biosynthesis of a novel family of glycosylated acyltrehalose lipooligosaccharides from Mycobacterium marinum. J Biol Chem 280: 4212442133.
  • Calamita, H., Ko, C., Tyagi, S., Yoshimatsu, T., Morrison, N.E., and Bishai, W.R. (2005) The Mycobacterium tuberculosis SigD sigma factor controls the expression of ribosome-associated gene products in stationary phase and is required for full virulence. Cell Microbiol 7: 233244.
  • Camus, J.C., Pryor, M.J., Medigue, C., and Cole, S.T. (2002) Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Microbiology 148: 29672973.
  • Carver, T.J., Rutherford, K.M., Berriman, M., Rajandream, M.A., Barrell, B.G., and Parkhill, J. (2005) ACT: the Artemis Comparison Tool. Bioinformatics 21: 34223423.
  • Casali, N., Konieczny, M., Schmidt, M.A., and Riley, L.W. (2002) Invasion activity of a Mycobacterium tuberculosis peptide presented by the Escherichia coli AIDA autotransporter. Infect Immun 70: 68466852.
  • Chang, J.C., Harik, N.S., Liao, R.P., and Sherman, D.R. (2007) Identification of mycobacterial genes that alter growth and pathology in macrophages and in mice. J Infect Dis (in press).
  • Chen, P., Ruiz, R.E., Li, Q., Silver, R.F., and Bishai, W.R. (2000) Construction and characterization of a Mycobacterium tuberculosis mutant lacking the alternate sigma factor gene, sigF. Infect Immun 68: 55755580.
  • Cole, S.T., Brosch, R., Parkhill, J., Garnier, T., Churcher, C., Harris, D., et al. (1998) Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Nature 393: 537544.
  • Corbett, E.L., Watt, C.J., Walker, N., Maher, D., Williams, B.G., Raviglione, M.C., and Dye, C. (2003) The growing burden of tuberculosis: global trends and interactions with the HIV epidemic. Arch Intern Med 163: 10091021.
  • Crooks, G.E., Hon, G., Chandonia, J.M., and Brenner, S.E. (2004) WebLogo: a sequence logo generator. Genome Res 14: 11881190.
  • Dobson, G., Minnikin, D.E., Minnikin, S.M., Parlett, J.H., Goodfellow, M., and Ridell, M.M.M. (1985) Systematic analysis of complex mycobacterial lipids. In Chemical Methods in Bacterial Systematics. Goodfellow, M. and Minnikin, D.E. (eds). London: Academic Press, pp. 237265.
  • Dover, L.G., Corsino, P.E., Daniels, I.R., Cocklin, S.L., Tatituri, V., Besra, G.S., and Futterer, K. (2004) Crystal structure of the TetR/CamR family repressor Mycobacterium tuberculosis EthR implicated in ethionamide resistance. J Mol Biol 340: 10951105.
  • Frenois, F., Engohang-Ndong, J., Locht, C., Baulard, A.R., and Villeret, V. (2004) Structure of EthR in a ligand bound conformation reveals therapeutic perspectives against tuberculosis. Mol Cell 16: 301307.
  • Gatfield, J., and Pieters, J. (2000) Essential role for cholesterol in entry of mycobacteria into macrophages. Science 288: 16471650.
  • Gomez, M., and Smith, I. (2000) Determinants of mycobacterial gene expression. In Molecular Genetics of Mycobacteria. Hatfull, G.F., and Jacobs, W.R. Jr (eds). Washington, DC: American Society for Microbiology Press, pp. 111129.
  • Grkovic, S., Brown, M.H., Roberts, N.J., Paulsen, I.T., and Skurray, R.A. (1998) QacR is a repressor protein that regulates expression of the Staphylococcus aureus multidrug efflux pump QacA. J Biol Chem 273: 1866518673.
  • Huffman, J.L., and Brennan, R.G. (2002) Prokaryotic transcription regulators: more than just the helix-turn-helix motif. Curr Opin Struct Biol 12: 98106.
  • Joshi, S.M., Pandey, A.K., Capite, N., Fortune, S.M., Rubin, E.J., and Sassetti, C.M. (2006) Characterization of mycobacterial virulence genes through genetic interaction mapping. Proc Natl Acad Sci USA 103: 1176011765.
  • Kendall, S.L., Rison, S.C., Movahedzadeh, F., Frita, R., and Stoker, N.G. (2004) What do microarrays really tell us about M. tuberculosis? Trends Microbiol 12: 537544.
  • Malhotra, V., Sharma, D., Ramanathan, V.D., Shakila, H., Saini, D.K., Chakravorty, S., et al. (2004) Disruption of response regulator gene, devR, leads to attenuation in virulence of Mycobacterium tuberculosis. FEMS Microbiol Lett 231: 237245.
  • Martin, C., Williams, A., Hernandez-Pando, R., Cardona, P.J., Gormley, E., Bordat, Y., et al. (2006) The live Mycobacterium tuberculosis phoP mutant strain is more attenuated than BCG and confers protective immunity against tuberculosis in mice and guinea pigs. Vaccine 24: 34083419.
  • McKinney, J.D., Honer zu Bentrup, K., Munoz-Elias, E.J., Miczak, A., Chen, B., Chan, W.T., et al. (2000) Persistence of Mycobacterium tuberculosis in macrophages and mice requires the glyoxylate shunt enzyme isocitrate lyase. Nature 406: 735738.
  • Mitra, D., Saha, B., Das, D., Wiker, H.G., and Das, A.K. (2005) Correlating sequential homology of Mce1A, Mce2A, Mce3A and Mce4A with their possible functions in mammalian cell entry of Mycobacterium tuberculosis performing homology modeling. Tuberculosis (Edinb) 85: 337345.
  • Orth, P., Schnappinger, D., Hillen, W., Saenger, W., and Hinrichs, W. (2000) Structural basis of gene regulation by the tetracycline inducible Tet repressor-operator system. Nat Struct Biol 7: 215219.
  • Parish, T., and Stoker, N.G. (1998) Electroporation of mycobacteria. Meth Mol Biol 101: 129144.
  • Parish, T., Smith, D.A., Roberts, G., Betts, J., and Stoker, N.G. (2003) The senX3-regX3 two-component regulatory system of Mycobacterium tuberculosis is required for virulence. Microbiology 149: 14231435.
  • Parish, T., and Stoker, N.G. (2000) Use of a flexible cassette method to generate a double unmarked Mycobacterium tuberculosis tlyA plcABC mutant by gene replacement. Microbiology 146: 19691975.
  • Perez, E., Samper, S., Bordas, Y., Guilhot, C., Gicquel, B., and Martin, C. (2001) An essential role for phoP. Mycobacterium tuberculosis virulence. Mol Microbiol 41: 179187.
  • Ramos, J.L., Martinez-Bueno, M., Molina-Henares, A.J., Teran, W., Watanabe, K., Zhang, X., et al. (2005) The TetR family of transcriptional repressors. Microbiol Mol Biol Rev 69: 326356.
  • Rao, V., Gao, F., Chen, B., Jacobs, W.R. Jr and Glickman, M.S. (2006) Trans-cyclopropanation of mycolic acids on trehalose dimycolate suppresses Mycobacterium tuberculosis-induced inflammation and virulence. J Clin Invest 116: 16601667.
  • Rengarajan, J., Bloom, B.R., and Rubin, E.J. (2005) Genome-wide requirements for Mycobacterium tuberculosis adaptation and survival in macrophages. Proc Natl Acad Sci USA 102: 83278332.
  • Reuter, M., Kupper, D., Meisel, A., Schroeder, C., and Kruger, D.H. (1998) Cooperative binding properties of restriction endonuclease EcoRII with DNA recognition sites. J Biol Chem 273: 82948300.
  • Rickman, L., Saldanha, J.W., Hunt, D.M., Hoar, D.N., Colston, M.J., Millar, J.B., and Buxton, R.S. (2004) A two-component signal transduction system with a PAS domain-containing sensor is required for virulence of Mycobacterium tuberculosis in mice. Biochem Biophys Res Commun 314: 259267.
  • Rosas-Magallanes, V., Stadthagen-Gomez, G., Rauzier, J., Barreiro, L.B., Tailleux, L., Boudou, F., et al. (2007) Signature-tagged transposon mutagenesis identifies novel Mycobacterium tuberculosis genes involved in the parasitism of human macrophages. Infect Immun 75: 504507.
  • Russell, D.G., Mwandumba, H.C., and Rhoades, E.E. (2002) Mycobacterium and the coat of many lipids. J Cell Biol 158: 421426.
  • Sandy, J., Mushtaq, A., Kawamura, A., Sinclair, J., Sim, E., and Noble, M. (2002) The structure of arylamine N-acetyltransferase from Mycobacterium smegmatis – an enzyme which inactivates the anti-tubercular drug, isoniazid. J Mol Biol 318: 10711083.
  • Santangelo, M.P., Goldstein, J., Alito, A., Gioffre, A., Caimi, K., Zabal, O., et al. (2002) Negative transcriptional regulation of the mce3 operon in Mycobacterium tuberculosis. Microbiology 148: 29973006.
  • Sassetti, C.M., and Rubin, E.J. (2003) Genetic requirements for mycobacterial survival during infection. Proc Natl Acad Sci USA 100: 1298912994.
  • Schnappinger, D., Ehrt, S., Voskuil, M.I., Liu, Y., Mangan, J.A., Monahan, I.M., et al. (2003) Transcriptional adaptation of Mycobacterium tuberculosis within macrophages: insights into the phagosomal environment. J Exp Med 198: 693704.
  • Schumacher, M.A., Miller, M.C., Grkovic, S., Brown, M.H., Skurray, R.A., and Brennan, R.G. (2001) Structural mechanisms of QacR induction and multidrug recognition. Science 294: 21582163.
  • Smyth, G.K. (2005) Limma: linear models for microarray data. In Bioinformatics and Computational Biology Solutions Using R and Bioconductor. Gentleman, R., Carey, V., Dudoit, S., Irizarry, R., and Huber, W. (eds). New York: Springer, pp. 397420.
  • Snapper, S.B. Melton, R.E. Mustafa, S. Kieser, T., and Jacobs, W.R. Jr (1990) Isolation and characterization of efficient plasmid transformation mutants of Mycobacterium smegmatis. Mol Microbiol 4: 19111919.
  • Sun, R. Converse, P.J. Ko, C. Tyagi, S. Morrison, N.E., and Bishai, W.R. (2004) Mycobacterium tuberculosis ECF sigma factor sigC is required for lethality in mice and for the conditional expression of a defined gene set. Mol Microbiol 52: 2538.
  • Talaat, A.M. Lyons, R. Howard, S.T., and Johnston, S.A. (2004) The temporal expression profile of Mycobacterium tuberculosis infection in mice. Proc Natl Acad Sci USA 101: 46024607.
  • Thompson, J.D. Higgins, D.G., and Gibson, T.J. (1994) CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res 22: 46734680.
  • Uchida, Y. Casali, N. White, A. Morici, L. Kendall, L.V., and Riley, L.W. (2007) Accelerated immunopathological response of mice infected with Mycobacterium tuberculosis disrupted in the mce1 operon negative transcriptional regulator. Cell Microbiol 9: 12751283.
  • Van der Geize, R. Yam, K. Heuser, T. Wilbrink, M.H. Hara, H. Anderton, M.C., et al. (2007) A gene cluster encoding cholesterol catabolism in a soil actinomycete provides insight into Mycobacterium tuberculosis survival in macrophages. Proc Natl Acad Sci USA 104: 19471952.
  • Walters, S.B., Dubnau, E., Kolesnikova, I., Laval, F., Daffe, M., and Smith, I. (2006) The Mycobacterium tuberculosis PhoPR two-component system regulates genes essential for virulence and complex lipid biosynthesis. Mol Microbiol 60: 312330.
  • Wernisch, L., Kendall, S.L., Soneji, S., Wietzorrek, A., Parish, T., Hinds, J., et al. (2003) Analysis of whole-genome microarray replicates using mixed models. Bioinformatics 19: 5361.
  • Zahrt, T.C., and Deretic, V. (2001) Mycobacterium tuberculosis signal transduction system required for persistent infections. Proc Natl Acad Sci USA 98: 1270612711.