SEARCH

SEARCH BY CITATION

References

  • Adhikari, R.P., and Novick, R.P. (2008) Regulatory organization of the staphylococcal sae locus. Microbiology 154: 949959.
  • Anderson, K.L., Roberts, C., Disz, T., Vonstein, V., Hwang, K., Overbeek, R., et al. (2006) Characterization of the Staphylococcus aureus heat shock, cold shock, stringent, and SOS responses and their effects on log-phase mRNA turnover. J Bacteriol 188: 67396756.
  • Anzaldi, L.L., and Skaar, E.P. (2010) Overcoming the heme paradox: heme toxicity and tolerance in bacterial pathogens. Infect Immun 78: 49774989.
  • Attia, A.S., Benson, M.A., Stauff, D.L., Torres, V.J., and Skaar, E.P. (2010) Membrane damage elicits an immunomodulatory program in Staphylococcus aureus. PLoS Pathog 6: e1000802.
  • Baba, T., Bae, T., Schneewind, O., Takeuchi, F., and Hiramatsu, K. (2008) Genome sequence of Staphylococcus aureus strain Newman and comparative analysis of staphylococcal genomes: polymorphism and evolution of two major pathogenicity islands. J Bacteriol 190: 300310.
  • Bateman, B.T., Donegan, N.P., Jarry, T.M., Palma, M., and Cheung, A.L. (2001) Evaluation of a tetracycline-inducible promoter in Staphylococcus aureus in vitro and in vivo and its application in demonstrating the role of sigB in microcolony formation. Infect Immun 69: 78517857.
  • Bestebroer, J., Poppelier, M.J., Ulfman, L.H., Lenting, P.J., Denis, C.V., van Kessel, K.P., et al. (2007) Staphylococcal superantigen-like 5 binds PSGL-1 and inhibits P-selectin-mediated neutrophil rolling. Blood 109: 29362943.
  • Bestebroer, J., van Kessel, K.P.M., Azouagh, H., Walenkamp, A.M., Boer, I.G.J., Romijn, R.A., et al. (2009) Staphylococcal SSL5 inhibits leukocyte activation by chemokines and anaphylatoxins. Blood 113: 328337.
  • Bestebroer, J., Aerts, P.C., Rooijakkers, S.H., Pandey, M.K., Kohl, J., van Strijp, J.A., and de Haas, C.J. (2010) Functional basis for complement evasion by staphylococcal superantigen-like 7. Cell Microbiol 12: 15061516.
  • Boisset, S., Geissmann, T., Huntzinger, E., Fechter, P., Bendridi, N., Possedko, M., et al. (2007) Staphylococcus aureus RNAIII coordinately represses the synthesis of virulence factors and the transcription regulator Rot by an antisense mechanism. Genes Dev 21: 13531366.
  • Boles, B.R., Thoendel, M., Roth, A.J., and Horswill, A.R. (2010) Identification of genes involved in polysaccharide-independent Staphylococcus aureus biofilm formation. PLoS ONE 5: e10146.
  • Booth, M.C., Atkuri, R.V., Nanda, S.K., Iandolo, J.J., and Gilmore, M.S. (1995) Accessory gene regulator controls Staphylococcus aureus virulence in endophthalmitis. Invest Ophthalmol Vis Sci 36: 18281836.
  • Bubeck Wardenburg, J., Williams, W.A., and Missiakas, D. (2006) Host defenses against Staphylococcus aureus infection require recognition of bacterial lipoproteins. Proc Natl Acad Sci USA 103: 1383113836.
  • Bubeck Wardenburg, J., Patel, R.J., and Schneewind, O. (2007) Surface proteins and exotoxins are required for the pathogenesis of Staphylococcus aureus pneumonia. Infect Immun 75: 10401044.
  • Cheung, A.L., Eberhardt, K.J., Chung, E., Yeaman, M.R., Sullam, P.M., Ramos, M., and Bayer, A.S. (1994) Diminished virulence of a sar-/agr- mutant of Staphylococcus aureus in the rabbit model of endocarditis. J Clin Invest 94: 18151822.
  • Cheung, A.L., Schmidt, K., Bateman, B., and Manna, A.C. (2001) SarS, a SarA homolog repressible by agr, is an activator of protein A synthesis in Staphylococcus aureus. Infect Immun 69: 24482455.
  • Cheung, A.L., Bayer, A.S., Zhang, G., Gresham, H., and Xiong, Y.Q. (2004) Regulation of virulence determinants in vitro and in vivo in Staphylococcus aureus. FEMS Immunol Med Microbiol 40: 19.
  • Chung, M.C., Wines, B.D., Baker, H., Langley, R.J., Baker, E.N., and Fraser, J.D. (2007) The crystal structure of staphylococcal superantigen-like protein 11 in complex with sialyl Lewis X reveals the mechanism for cell binding and immune inhibition. Mol Microbiol 66: 13421355.
  • Cirz, R.T., Jones, M.B., Gingles, N.A., Minogue, T.D., Jarrahi, B., Peterson, S.N., and Romesberg, F.E. (2007) Complete and SOS-mediated response of Staphylococcus aureus to the antibiotic ciprofloxacin. J Bacteriol 189: 531539.
  • Cooper, JE, and Feil, EJ (2006) The phylogeny of Staphylococcus aureus – which genes make the best intra-species markers? Microbiology 152: 12971305.
  • Corbin, B.D., Seeley, E.H., Raab, A., Feldmann, J., Miller, M.R., Torres, V.J., et al. (2008) Metal Chelation and Inhibition of Bacterial Growth in Tissue Abscesses. Science 319: 962965.
  • Delgado, A., Zaman, S., Muthaiyan, A., Nagarajan, V., Elasri, M.O., Wilkinson, B.J., and Gustafson, J.E. (2008) The fusidic acid stimulon of Staphylococcus aureus. J Antimicrob Chemother 62: 12071214.
  • Dunman, P.M., Murphy, E., Haney, S., Palacios, D., Tucker-Kellogg, G., Wu, S., et al. (2001) Transcription profiling-based identification of Staphylococcus aureus genes regulated by the agr and/or sarA loci. J Bacteriol 183: 73417353.
  • Duthie, E.S., and Lorenz, L.L. (1952) Staphylococcal coagulase; mode of action and antigenicity. J Gen Microbiol 6: 95107.
  • Felden, B., Vandenesch, F., Bouloc, P., and Romby, P. (2011) The Staphylococcus aureus RNome and Its Commitment to Virulence. PLoS Pathog 7: e1002006.
  • Foster, T.J. (2005) Immune evasion by staphylococci. Nat Rev Microbiol 3: 948958.
  • Fowler, V.G., Jr, Sakoulas, G., McIntyre, L.M., Meka, V.G., Arbeit, R.D., Cabell, C.H., et al. (2004) Persistent bacteremia due to methicillin-resistant Staphylococcus aureus infection is associated with agr dysfunction and low-level in vitro resistance to thrombin-induced platelet microbicidal protein. J Infect Dis 190: 11401149.
  • Fraser, J.D., and Proft, T. (2008) The bacterial superantigen and superantigen-like proteins. Immunol Rev 225: 226243.
  • Gao, J., and Stewart, G.C. (2004) Regulatory elements of the Staphylococcus aureus protein A (Spa) promoter. J Bacteriol 186: 37383748.
  • Geisinger, E., Adhikari, R.P., Jin, R., Ross, H.F., and Novick, R.P. (2006) Inhibition of rot translation by RNAIII, a key feature of agr function. Mol Microbiol 61: 10381048.
  • Geisinger, E., Muir, T.W., and Novick, R.P. (2009) agr receptor mutants reveal distinct modes of inhibition by staphylococcal autoinducing peptides. Proc Natl Acad Sci USA 106: 12161221.
  • Gillaspy, A.F., Hickmon, S.G., Skinner, R.A., Thomas, J.R., Nelson, C.L., and Smeltzer, M.S. (1995) Role of the accessory gene regulator (agr) in pathogenesis of staphylococcal osteomyelitis. Infect Immun 63: 33733380.
  • Giraudo, A.T., Raspanti, C.G., Calzolari, A., and Nagel, R. (1994) Characterization of a Tn551-mutant of Staphylococcus aureus defective in the production of several exoproteins. Can J Microbiol 40: 677681.
  • Giraudo, A.T., Calzolari, A., Cataldi, A.A., Bogni, C., and Nagel, R. (1999) The sae locus of Staphylococcus aureus encodes a two-component regulatory system. FEMS Microbiol Lett 177: 1522.
  • Graves, S.F., Kobayashi, S.D., and DeLeo, F.R. (2010) Community-associated methicillin-resistant Staphylococcus aureus immune evasion and virulence. J Mol Med 88: 109114.
  • Herbert, S., Bera, A., Nerz, C., Kraus, D., Peschel, A., Goerke, C., et al. (2007) Molecular basis of resistance to muramidase and cationic antimicrobial peptide activity of lysozyme in staphylococci. PLoS Pathog 3: e102.
  • Hsieh, H.-Y., Tseng, C.W., and Stewart, G.C. (2008) Regulation of Rot Expression in Staphyloccus aureus. J Bacteriol 190: 546554.
  • Itoh, S., Hamada, E., Kamoshida, G., Yokoyama, R., Takii, T., Onozaki, K., and Tsuji, T. (2010) Staphylococcal superantigen-like protein 10 (SSL10) binds to human immunoglobulin G (IgG) and inhibits complement activation via the classical pathway. Mol Immunol 47: 932938.
  • Jelsbak, L., Hemmingsen, L., Donat, S., Ohlsen, K., Boye, K., Westh, H., et al. (2010) Growth phase-dependent regulation of the global virulence regulator Rot in clinical isolates of Staphylococcus aureus. Int J Med Microbiol 300: 229236.
  • Kielian, T., Cheung, A., and Hickey, W.F. (2001) Diminished virulence of an alpha-toxin mutant of Staphylococcus aureus in experimental brain abscesses. Infect Immun 69: 69026911.
  • Klevens, R.M., Morrison, M.A., Nadle, J., Petit, S., Gershman, K., Ray, S., et al. (2007) Invasive methicillin-resistant Staphylococcus aureus infections in the United States. JAMA 298: 17631771.
  • Kreiswirth, B.N., Lofdahl, S., Betley, M.J., O'Reilly, M., Schlievert, P.M., Bergdoll, M.S., and Novick, R.P. (1983) The toxic shock syndrome exotoxin structural gene is not detectably transmitted by a prophage. Nature 305: 709712.
  • Larkin, M.A., Blackshields, G., Brown, N.P., Chenna, R., McGettigan, P.A., McWilliam, H., Valentin, F., Wallace, I.M., Wilm, A., Lopez, R., Thompson, J.D., Gibson, T.J., and Higgins, D.G. (2007) ClustalW and ClustalX version 2. Bioinformatics 23(21): 29472948.
  • Langley, R., Wines, B., Willoughby, N., Basu, I., Proft, T., and Fraser, J.D. (2005) The staphylococcal superantigen-like protein 7 binds IgA and complement C5 and inhibits IgA-Fc alpha RI binding and serum killing of bacteria. J Immunol 174: 29262933.
  • Lauderdale, K.J., Malone, C.L., Boles, B.R., Morcuende, J., and Horswill, A.R. (2009) Biofilm dispersal of community-associated methicillin-resistant Staphylococcus aureus on orthopedic implant material. J Orthop Res 28: 5561.
  • Lauderdale, K.J., Malone, C.L., Boles, B.R., Morcuende, J., and Horswill, A.R. (2010) Biofilm dispersal of community-associated methicillin-resistant Staphylococcus aureus on orthopedic implant material. J Orthop Res 28: 5561.
  • Li, D., and Cheung, A. (2008) Repression of hla by rot is dependent on sae in Staphylococcus aureus. Infect Immun 76: 10681075.
  • Liang, X., Zheng, L., Landwehr, C., Lunsford, D., Holmes, D., and Ji, Y. (2005) Global regulation of gene expression by ArlRS, a two-component signal transduction regulatory system of Staphylococcus aureus. J Bacteriol 187: 54865492.
  • McNamara, P.J., and Bayer, A.S. (2005) A rot mutation restores parental virulence to an agr-null Staphylococcus aureus strain in a rabbit model of endocarditis. Infect Immun 73: 38063809.
  • McNamara, P.J., Milligan-Monroe, K.C., Khalili, S., and Proctor, R.A. (2000) Identification, Cloning, and Initial Characterization of rot, a Locus Encoding a Regulator of Virulence Factor Expression in Staphylococcus aureus. J Bacteriol 182: 31973203.
  • Manna, A.C., and Ray, B. (2007) Regulation and characterization of rot transcription in Staphylococcus aureus. Microbiology 153: 15381545.
  • Nagarajan, V., and Elasri, M.O. (2007) SAMMD: Staphylococcus aureus microarray meta-database. BMC Genomics 8: 351.
  • Nizet, V. (2007) Understanding how leading bacterial pathogens subvert innate immunity to reveal novel therapeutic targets. J Allergy Clin Immunol 120: 1322.
  • Novick, R.P. (1990) The staphylococcus as a molecular genetic system. In Molecular Biology of the Staphylococci. Novick, R.P. (ed.). New York: VCH Publishers, pp. 137.
  • Novick, R.P. (2003) Autoinduction and signal transduction in the regulation of staphylococcal virulence. Mol Microbiol 48: 14291449.
  • Novick, R.P., and Geisinger, E. (2008) Quorum sensing in staphylococci. Annu Rev Genet 42: 541564.
  • Novick, R.P., Projan, S., Kornblum, J., Ross, H., Kreiswirth, B., and Moghazeh, S. (1995) The agr P-2 operon: an autocatalytic sensory transduction system in Staphylococcus aureus. Mol Gen Genet 248: 446458.
  • Nygaard, T.K., Pallister, K.B., Ruzevich, P., Griffith, S., Vuong, C., and Voyich, J.M. (2010) SaeR binds a consensus sequence within virulence gene promoters to advance USA300 pathogenesis. J Infect Dis 201: 241254.
  • Olson, P.D., Kuechenmeister, L.J., Anderson, K.L., Daily, S., Beenken, K.E., Roux, C.M., et al. (2011) Small molecule inhibitors of Staphylococcus aureus RnpA alter cellular mRNA turnover, exhibit antimicrobial activity, and attenuate pathogenesis. PLoS Pathog 7: e1001287.
  • Oscarsson, J., Harlos, C., and Arvidson, S. (2005) Regulatory role of proteins binding to the spa (protein A) and sarS (staphylococcal accessory regulator) promoter regions in Staphylococcus aureus NTCC 8325-4. Int J Med Microbiol 295: 253266.
  • Oscarsson, J., Tegmark-Wisell, K., and Arvidson, S. (2006) Coordinated and differential control of aureolysin (aur) and serine protease (sspA) transcription in Staphylococcus aureus by sarA, rot and agr (RNAIII). Int J Med Microbiol 296: 365380.
  • Palazzolo-Ballance, A.M., Reniere, M.L., Braughton, K.R., Sturdevant, D.E., Otto, M., Kreiswirth, B.N., et al. (2008) Neutrophil microbicides induce a pathogen survival response in community-associated methicillin-resistant Staphylococcus aureus. J Immunol 180: 500509.
  • Pantrangi, M., Singh, V.K., Wolz, C., and Shukla, S.K. (2010) Staphylococcal superantigen-like genes, ssl5 and ssl8, are positively regulated by Sae and negatively by Agr in the Newman strain. FEMS Microbiol Lett 308: 175184.
  • Peterson, M.M., Mack, J.L., Hall, P.R., Alsup, A.A., Alexander, S.M., Sully, E.K., et al. (2008) Apolipoprotein B Is an innate barrier against invasive Staphylococcus aureus infection. Cell Host Microbe 4: 555566.
  • Pishchany, G., McCoy, A.L., Torres, V.J., Krause, J.C., Crowe, J.E., Jr, Fabry, M.E., and Skaar, E.P. (2010) Specificity for human hemoglobin enhances Staphylococcus aureus infection. Cell Host Microbe 8: 544550.
  • Queck, S.Y., Jameson-Lee, M., Villaruz, A.E., Bach, T.H., Khan, B.A., Sturdevant, D.E., et al. (2008) RNAIII-independent target gene control by the agr quorum-sensing system: insight into the evolution of virulence regulation in Staphylococcus aureus. Mol Cell 32: 150158.
  • Rothfork, J.M., Timmins, G.S., Harris, M.N., Chen, X., Lusis, A.J., Otto, M., et al. (2004) Inactivation of a bacterial virulence pheromone by phagocyte-derived oxidants: new role for the NADPH oxidase in host defense. Proc Natl Acad Sci USA 101: 1386713872.
  • Said-Salim, B., Dunman, P.M., McAleese, F.M., Macapagal, D., Murphy, E., McNamara, P.J., et al. (2003) Global Regulation of Staphylococcus aureus Genes by Rot. J Bacteriol 185: 610619.
  • Schneewind, O., Model, P., and Fischetti, V.A. (1992) Sorting of protein A to the staphylococcal cell wall. Cell 70: 267281.
  • Shopsin, B., Gomez, M., Montgomery, S.O., Smith, D.H., Waddington, M., Dodge, D.E., et al. (1999) Evaluation of protein A gene polymorphic region DNA sequencing for typing of Staphylococcus aureus strains. J Clin Microbiol 37: 35563563.
  • Shopsin, B., Mathema, B., Martinez, J., Ha, E., Campo, M.L., Fierman, A., et al. (2000) Prevalence of methicillin-resistant and methicillin-susceptible Staphylococcus aureus in the community. J Infect Dis 182: 359362.
  • Shopsin, B., Drlica-Wagner, A., Mathema, B., Adhikari, R.P., Kreiswirth, B.N., and Novick, R.P. (2008) Prevalence of agr dysfunction among colonizing Staphylococcus aureus strains. J Infect Dis 198: 11711174.
  • Shopsin, B., Eaton, C., Wasserman, G.A., Mathema, B., Adhikari, R.P., Agolory, S., et al. (2010) Mutations in agr do not persist in natural populations of methicillin-resistant Staphylococcus aureus. J Infect Dis 202: 15931599.
  • Skaar, E.P., Humayun, M., Bae, T., DeBord, K.L., and Schneewind, O. (2004) Iron-source preference of Staphylococcus aureus infections. Science 305: 16261628.
  • Stauff, D.L., Torres, V.J., and Skaar, E.P. (2007) Signaling and DNA-binding activities of the Staphylococcus aureus HssR-HssS two-component system required for heme sensing. J Biol Chem 282: 2611126121.
  • Sun, F., Li, C., Jeong, D., Sohn, C., He, C., and Bae, T. (2010) In the Staphylococcus aureus two-component system sae, the response regulator SaeR binds to a direct repeat sequence and DNA binding requires phosphorylation by the sensor kinase SaeS. J Bacteriol 192: 21112127.
  • Tegmark, K., Karlsson, A., and Arvidson, S. (2000) Identification and characterization of SarH1, a new global regulator of virulence gene expression in Staphylococcus aureus. Mol Microbiol 37: 398409.
  • Thoendel, M., Kavanaugh, J.S., Flack, C.E., and Horswill, A.R. (2011) Peptide signaling in the staphylococci. Chem Rev 111: 117151.
  • Torres, V.J., Stauff, D.L., Pishchany, G., Bezbradica, J.S., Gordy, L.E., Iturregui, J., et al. (2007) A Staphylococcus aureus regulatory system that responds to host heme and modulates virulence. Cell Host Microbe 1: 109119.
  • Torres, V.J., Attia, A.S., Mason, W.J., Hood, M.I., Corbin, B.D., Beasley, F.C., et al. (2010) Staphylococcus aureus fur regulates the expression of virulence factors that contribute to the pathogenesis of pneumonia. Infect Immun 78: 16181628.
  • Traber, K., and Novick, R. (2006) A slipped-mispairing mutation in AgrA of laboratory strains and clinical isolates results in delayed activation of agr and failure to translate delta- and alpha-haemolysins. Mol Microbiol 59: 15191530.
  • Traber, K.E., Lee, E., Benson, S., Corrigan, R., Cantera, M., Shopsin, B., and Novick, R.P. (2008) agr function in clinical Staphylococcus aureus isolates. Microbiology 154: 22652274.
  • Tseng, C.W., and Stewart, G.C. (2005) Rot repression of enterotoxin B expression in Staphylococcus aureus. J Bacteriol 187: 53015309.
  • Tseng, C.W., Zhang, S., and Stewart, G.C. (2004) Accessory gene regulator control of staphyloccoccal enterotoxin d gene expression. J Bacteriol 186: 17931801.
  • Voyich, J.M., Braughton, K.R., Sturdevant, D.E., Whitney, A.R., Said-Salim, B., Porcella, S.F., et al. (2005) Insights into Mechanisms Used by Staphylococcus aureus to Avoid Destruction by Human Neutrophils. J Immunol 175: 39073919.
  • Vuong, C., Kocianova, S., Yao, Y., Carmody, A.B., and Otto, M. (2004) Increased colonization of indwelling medical devices by quorum-sensing mutants of Staphylococcus epidermidis in vivo. J Infect Dis 190: 14981505.
  • Wang, L., Trawick, J.D., Yamamoto, R., and Zamudio, C. (2004) Genome-wide operon prediction in Staphylococcus aureus. Nucleic Acids Res 32: 36893702.
  • Weinrick, B., Dunman, P.M., McAleese, F., Murphy, E., Projan, S.J., Fang, Y., and Novick, R.P. (2004) Effect of mild acid on gene expression in Staphylococcus aureus. J Bacteriol 186: 84078423.
  • Wines, B.D., Willoughby, N., Fraser, J.D., and Hogarth, P.M. (2006) A Competitive Mechanism for Staphyloccoal Toxin SSL7 Inhibiting the Leukocyte IgA Receptor, FcaRI, is Revealed by SSL7 binding at the Ca2/Ca3 interface of IgA. J Biol Chem 281: 13891393.
  • Wright, J.S., 3rd, Jin, R., and Novick, R.P. (2005) Transient interference with staphylococcal quorum sensing blocks abscess formation. Proc Natl Acad Sci USA 102: 16911696.
  • Yarwood, J.M., McCormick, J.K., Paustian, M.L., Kapur, V., and Schlievert, P.M. (2002) Repression of the Staphylococcus aureus accessory gene regulator in serum and in vivo. J Bacteriol 184: 10951101.
  • Yarwood, J.M., Bartels, D.J., Volper, E.M., and Greenberg, E.P. (2004) Quorum sensing in Staphylococcus aureus biofilms. J Bacteriol 186: 18381850.