• 1
    Rescorla RA. Behavioral studies of Pavlovian conditioning. Ann Rev Neurosci 1988; 11: 32952.
  • 2
    Bjorkstrand PA. Effects of conditioned stimulus pre-exposure on human electrodermal conditioning to fear-relevant and fear-irrelevant stimuli. Biol Psychol 1990; 30: 3550.
  • 3
    Dadds MR, Bovbjerg DH, Redd WH, Cutmore TR. Imagery in human classical conditioning. Psychol Bull 1997; 122: 89103.
  • 4
    Cameron OG. Interception: the inside story—a model for psychosomatic processes. Psychosom Med 2001; 63: 697710.
  • 5
    Rao SS, Hatfield RA, Suls JM, Chamberlain MJ. Psychological and physical stress induce differential effects on human colonic motility. Am J Gastroenterol 1998; 93: 98590.
    Direct Link:
  • 6
    Fukudo S, Nomura T, Muranaka M, Taguchi F. Brain-gut response to stress and cholinergic stimulation in irritable bowel syndrome. A preliminary study. J Clin Gastroenterol 1993; 17: 13341.
  • 7
    Stam R, Croiset G, Akkermans LM, Wiegant VM. Effects of novelty and conditioned fear on small intestinal and colonic motility and behaviour in the rat. Physiol Behav 1995; 58: 8039.
  • 8
    Irwin C, Falsetti SA, Lydiard RB et al. Comorbidity of posttraumatic stress disorder and irritable bowel syndrome. Clin Psychiatry 1996; 57: 5768.
  • 9
    Drossman DA, Leserman J, Nachman G et al. Sexual and physical abuse in women with functional or organic gastrointestinal disorders. Ann Intern Med 1990; 113: 82833.
  • 10
    Bremner JD, Vythilingam M, Vermetten E et al. Cortisol response to a cognitive stress challenge in posttraumatic stress disorder (PTSD) related to childhood abuse. Psychoneuroendocrinology 2003; 28: 73350.
  • 11
    Stam R, Akkermans LM, Wiegant VM. Trauma and the gut: interactions between stressful experience and intestinal function. Gut 1997; 40: 7049.
  • 12
    Fredrikson M, Wik G, Fischer H, Andersson J. Affective and attentive neural networks in humans: a PET study of Pavlovian conditioning. Neuroreport 1995; 7: 97101.
  • 13
    Hugdahl K, Berardi A, Thompson WL et al. Brain mechanisms in human classical conditioning: a PET blood flow study. Neuroreport 1995; 6: 17238.
  • 14
    Fischer H, Andersson JL, Furmark T, Fredrikson M. Fear conditioning and brain activity: a positron emission tomography study in humans. Behav Neurosci 2000; 114: 67180.
  • 15
    Naliboff BD, Derbyshire SW, Munakata J et al. Cerebral activation in patients with irritable bowel syndrome and control subjects during rectosigmoid stimulation. Psychosom Med 2001; 63: 36575.
  • 16
    Kandel ER, Kupfermann I, Iversen S. Learning and memory. In: KandelER, ScwartzJH, JessellTM, eds. Principles of Neural Science, 4th edn. New York: McGraw-Hill, 2000: 122747.
  • 17
    Bell AM, Pemberton JH, Hanson RB, Zinsmeister AR. Variations in muscle tone of the human rectum: recordings with an electromechanical barostat. Am J Physiol 1991; 260: G1725.
  • 18
    von der Ohe, Hanson RB, Camilleri M. Comparison of stimultaneous recordings of human colonic constructions by manometry and a barostat. Neurogastroenterol Motil 1994; 6: 21322.
  • 19
    Whitehead WE, Delvaux M. Standardization of barostat procedures for testing smooth muscle tone and sensory thresholds in the gastrointestinal tract. Dig Dis Sci 1997; 42: 22341.
  • 20
    Hamaguchi T, Kano M, Rikimaru H et al. Brain activity during distention of the descending colon in humans. Neurogastroenterol Motil 2004; 16: 299309.
  • 21
    Fujiwara T, Watanuki S, Yamamoto S et al. Performance evaluation of a large axial field-of-view PET scanner: SET-2400W. Ann Nucl Med 1997; 11: 30713.
  • 22
    Cherry SR, Dahlbom M, Hoffman EJ. Evaluation of a 3D reconstruction algorithm for multi-slice PET scanners. Phys Med Biol 1992; 37: 77990.
  • 23
    Friston KJ, Frith CD, Liddle PF, Frackowiak RS. Comparing functional (PET) images: the assessment of significant change. J Cereb Blood Flow Metab 1991; 11: 6909.
  • 24
    Mertz H, Fullerton S, Naliboff B, Mayer EA. Symptoms and visceral perception in severe functional and organic dyspepsia. Gut 1998; 42: 81422.
  • 25
    Obrist PA, Wood DM, Perez-Reyes M. Heart rate during conditioning in humans: effects of UCS intensity, vagal blockade, and adrenergic block of vasomotor activity. J Exp Psychol 1965; 70: 3242.
  • 26
    Santibanez-H G, Schroeder H. Does heart rate differentiate neurotic from normal people in conditioned reflex test? Pavlov J Biol Sci 1988; 23: 1521.
  • 27
    Kalin NH, Shelton SE, Davidson RJ et al. A new method for aversive Pavlovian conditioning of heart rate in rhesus monkey. Physiol Behav 1996; 60: 10436.
  • 28
    Iwata J, LeDoux JE. Dissociation of associative and nonassociative concomitants of classical fear conditioning in the freely behaving rat. Behav Neurosci 1988; 102: 6676.
  • 29
    Nijsen MJ, Croiset G, Diamant M et al. Conditioned fear-induced tachycardia in the rat: vagal involvement. Eur J Pharmacol 1998; 350: 21122.
  • 30
    Fukudo S, Suzuki J. Colonic motility, autonomic function, and gastrointestinal hormones under psychological stress on irritable bowel syndrome. Tohoku J Exp Med 1987; 151: 37385.
  • 31
    Gue M, Junien JL, Bueno L. Conditioned emotional response in rats enhances colonic motility through the central release of corticotropin-releasing factor. Gastroenterology 1991; 100: 96470.
  • 32
    Derbyshire SW, Jones AK, Gyulai F et al. Pain processing during three levels of noxious stimulation produces differential patterns of central activity. Pain 1997; 73: 43145.
  • 33
    Bantick SJ, Wise RG, Ploghaus A et al. Imaging how attention modulates pain in humans using functional MRI. Brain 2002; 125: 31019.
  • 34
    Bernstein CN, Frankenstein UN, Rawsthorne P et al. Cortical mapping of visceral pain in patients with GI disorders using functional magnetic resonance imaging. Am J Gastroenterol 2002; 97: 31927.
    Direct Link:
  • 35
    Sawamoto N, Honda M, Okada T et al. Expectation of pain enhances responses to nonpainful somatosensory stimulation in the anterior cingulate cortex and parietal operculum/posterior insula: an event-related functional magnetic resonance imaging study. J Neurosci 2000; 20: 743845.
  • 36
    Augustine JR. Circuitry and functional aspects of the insular lobe in primates including humans. Brain Res Rev 1996; 22: 22944.
  • 37
    Porro CA, Cettolo V, Francescato MP, Baraldi P. Temporal and intensity coding of pain in human cortex. J Neurophysiol 1998; 80: 331220.
  • 38
    Ploghaus A, Tracey I, Gati JS et al. Dissociating pain from its anticipation in the human brain. Science 1999; 284: 197981.
  • 39
    Lee OY, Mayer EA, Schmulson M, Chang L, Naliboff B. Gender-related differences in IBS symptoms. Am J Gastroenterol 2001; 96: 218493.
    Direct Link:
  • 40
    Chiarioni G, Bassotti G, Germani U et al. Idiopathic megarectum in adults. An assessment of manometric and radiological variables. Dig Dis Sci 1995; 40: 228692.
  • 41
    Felt-Bersma RJ, Sloots CE, Poen AC et al. Rectal compliance as a routine measurement: extreme volumes have direct clinical imp act and normal volumes exclude rectum as a problem. Dis Colon Rectum 2000; 43: 17328.