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The reason for failure of on-demand PPI therapy in NERD patients

  1. E. Savarino,
  2. P. Zentilin,
  3. V. Savarino

Article first published online: 15 JUL 2011

DOI: 10.1111/j.1365-2982.2011.01722.x

Issue

Neurogastroenterology & Motility

Neurogastroenterology & Motility

Volume 23, Issue 8, page 811, August 2011

Additional Information

How to Cite

Savarino, E., Zentilin, P. and Savarino, V. (2011), The reason for failure of on-demand PPI therapy in NERD patients. Neurogastroenterology & Motility, 23: 811. doi: 10.1111/j.1365-2982.2011.01722.x

Author Information

  1. Division of Gastroenterology, Department of Internal Medicine, University of Genoa, Genoa, Italy

Publication History

  1. Issue published online: 15 JUL 2011
  2. Article first published online: 15 JUL 2011

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References

  • 1
    Wu JCY, Lai LH, Chow DKL et al. Concomitant irritable bowel syndrome is associated with failure of step-down on-demand proton pump inhibitor treatment in patients with gastro-esophageal reflux disease. Neurogastroenterol Motil 2011; 23: 155-e31.
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  • 2
    Savarino E, Pohl D, Zentilin P et al. Functional heartburn has more in common with functional dyspepsia than with non-erosive reflux disease. Gut 2009; 58: 1185–91.
  • 3
    Tack J, Talley NJ, Camilleri M et al. Functional gastroduodenal disorders. Gastroenterology 2006; 130: 1466–79.
  • 4
    Savarino E, Zentilin P, Tutuian R et al. The role of non-acid reflux in NERD: lessons learned from impedance-pH monitoring in 150 patients off therapy. Am J Gastroenterol 2008; 103: 2685–93.
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  • 5
    Mainie I, Tutuian R, Shay S et al. Acid and non-acid reflux in patients with persistent symptoms despite acid suppressive therapy: a multicenter study using combined ambulatory impedance-pH monitoring. Gut 2006; 55: 1398–402.
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