Descriptive epidemiology of congenital heart disease in Northern England

  1. Payam Dadvand1,2,
  2. Judith Rankin1,
  3. Mark D. F. Shirley1,2,
  4. Stephen Rushton1,2,
  5. Tanja Pless-Mulloli1

Article first published online: 12 NOV 2008

DOI: 10.1111/j.1365-3016.2008.00987.x

Issue

Paediatric and Perinatal Epidemiology

Paediatric and Perinatal Epidemiology

Volume 23, Issue 1, pages 58–65, January 2009

Additional Information

How to Cite

Dadvand, P., Rankin, J., Shirley, M. D. F., Rushton, S. and Pless-Mulloli, T. (2009), Descriptive epidemiology of congenital heart disease in Northern England. Paediatric and Perinatal Epidemiology, 23: 58–65. doi: 10.1111/j.1365-3016.2008.00987.x

Author Information

  1. 1

    Institute of Health and Society, and

  2. 2

    Institute for Research on Environment and Sustainability, Newcastle University, Newcastle upon Tyne, UK

*Payam Dadvand, MD, Institute of Health and Society, William Leech Building, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK. E-mail: payam.dadvand@ncl.ac.uk

Publication History

  1. Issue published online: 27 NOV 2008
  2. Article first published online: 12 NOV 2008

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Keywords:

  • congenital heart disease;
  • congenital malformations;
  • time trends

Summary

Congenital heart disease (CHD) is the most prevalent group of congenital anomalies. There is considerable variation in the reported epidemiology of CHD, mainly attributable to methodological differences. Using register-based data, the current study describes the epidemiology of CHD in a geographically well-defined population of the North of England during 1985–2003.

The total prevalence of CHD was 85.9 per 10 000 births and terminations of pregnancy for fetal anomaly. Livebirth prevalence was 79.7 per 10 000 livebirths. Both total and livebirth prevalence increased during the study period. Ninety-two per cent of affected pregnancies resulted in a livebirth, 5% were terminated, 2% resulted in a stillbirth, and 1% in a late miscarriage. Almost a quarter (23%) of cases had one or more coincident anomalies of other organs, with chromosomal abnormalities the most frequent group. A total of 89.2% of cases survived to 1 year and the survival improved during the study period. This population-based study has demonstrated an increasing trend in both prevalence and survival among children with CHD.

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