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Monospecific antibodies to 4 individual immunogenic components of a commercial PHA preparation were raised by immunization with the precipitates from crossed immunoelectrophoresis. The antibodies were used to prepare immunosorbents, which were then employed for the purification of individual PHA components. The results show that all the mitogenic and haemag-glutinating activity of the crude PHA resides in one of the 4 immunogenic components.