Role of plant CBP/p300-like genes in the regulation of flowering time
Article first published online: 27 NOV 2006
The Plant Journal
Volume 49, Issue 1, pages 103–114, January 2007
How to Cite
Han, S.-K., Song, J.-D., Noh, Y.-S. and Noh, B. (2007), Role of plant CBP/p300-like genes in the regulation of flowering time. The Plant Journal, 49: 103–114. doi: 10.1111/j.1365-313X.2006.02939.x
- Issue published online: 27 NOV 2006
- Article first published online: 27 NOV 2006
- Received 30 June 2006; revised 4 September 2006; accepted 13 September 2006.
- CREB-binding protein/p300;
- histone acetyltransferase;
- Histone deacetylase;
- FLOWERING LOCUS C;
CREB-binding protein (CBP) and its homolog p300 possess histone acetyltransferase activity and function as key transcriptional co-activators in the regulation of gene expression that controls differentiation and development in animals. However, the role of CBP/p300-like genes in plants has not yet been elucidated. Here, we show that Arabidopsis CBP/p300-like genes promote flowering by affecting the expression of a major floral repressor FLOWERING LOCUS C (FLC). Although animal CBP and p300 generally function as co-activators, Arabidopsis CBP/p300-like proteins are required for the negative regulation of FLC. This CBP/p300-mediated FLC repression may involve reversible protein acetylation independent of histone modification within FLC chromatin.