The ubiquitin-proteasome system regulates plant hormone signaling
Article first published online: 10 MAR 2010
© 2010 The Authors. Journal compilation © 2010 Blackwell Publishing Ltd
The Plant Journal
Special Issue: SPECIAL ISSUE Arabidopsis: A rich harvest 10 years after completion of the genome sequence
Volume 61, Issue 6, pages 1029–1040, March 2010
How to Cite
Santner, A. and Estelle, M. (2010), The ubiquitin-proteasome system regulates plant hormone signaling. The Plant Journal, 61: 1029–1040. doi: 10.1111/j.1365-313X.2010.04112.x
- Issue published online: 10 MAR 2010
- Article first published online: 10 MAR 2010
- Received 4 October 2009; revised 18 November 2009; accepted 24 November 2009.
- hormone signaling;
- ubiquitin-proteasome system
Plants utilize the ubiquitin-proteasome system (UPS) to modulate nearly every aspect of growth and development. Ubiquitin is covalently attached to target proteins through the action of three enzymes known as E1, E2, and E3. The ultimate outcome of this post-translational modification depends on the nature of the ubiquitin linkage and the extent of polyubiquitination. In most cases, ubiquitination results in degradation of the target protein in the 26S proteasome. During the last 10 years it has become clear that the UPS plays a prominent regulatory role in hormone biology. E3 ubiquitin ligases in particular actively participate in hormone perception, de-repression of hormone signaling pathways, degradation of hormone specific transcription factors, and regulation of hormone biosynthesis. It is certain that additional functions will be discovered as more of the nearly 1200 potential E3s in plants are elucidated.