TFL2/LHP1 is involved in auxin biosynthesis through positive regulation of YUCCA genes
Article first published online: 19 JAN 2011
© 2011 The Authors. The Plant Journal © 2011 Blackwell Publishing Ltd
The Plant Journal
Volume 65, Issue 6, pages 897–906, March 2011
How to Cite
Rizzardi, K., Landberg, K., Nilsson, L., Ljung, K. and Sundås-Larsson, A. (2011), TFL2/LHP1 is involved in auxin biosynthesis through positive regulation of YUCCA genes. The Plant Journal, 65: 897–906. doi: 10.1111/j.1365-313X.2010.04470.x
- Issue published online: 21 MAR 2011
- Article first published online: 19 JAN 2011
- Accepted manuscript online: 24 DEC 2010 10:09AM EST
- Received 19 February 2010; revised 1 December 2010; accepted 19 December 2010; published online 19 January 2011.
- TERMINAL FLOWER2/LIKE HETEROCHROMATIN PROTEIN1;
- auxin response;
- auxin biosynthesis;
TERMINAL FLOWER2 (TFL2) is the plant homologue of metazoan HETEROCHROMATIN PROTEIN1 (HP1) protein family. It is known that, unlike most HP1 proteins, TFL2 does not primarily localize to heterochromatin; instead it functions in regulation of specific genes in euchromatic regions. We show that the tfl2 mutant has a lower rate of auxin biosynthesis, resulting in low levels of auxin. In line with this, tfl2 mutants have lower levels of expression of auxin response genes and retain an auxin response. The reduced rate of auxin biosynthesis in tfl2 is correlated to the down-regulation of specific genes in the tryptophan-dependent auxin biosynthesis pathway, a sub-set of the YUCCA genes. In vivo, TFL2 is targeted to a number of the YUCCA genes in an auxin-dependent fashion revealing a role of TFL2 in auxin regulation, probably as a component of protein complexes affecting transcriptional control.