PSEUDOPELADE: AN INHERITED ALOPECIA

Authors

  • WILLIAM J. SAHL M.D.

    Corresponding author
    1. From Private Practice.
      Address for correspondence: William J. Sahl, M.D., Skin Medicine and Surgery Centers, 43 Jefferson Blvd., Warwick, RI 02888.
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Address for correspondence: William J. Sahl, M.D., Skin Medicine and Surgery Centers, 43 Jefferson Blvd., Warwick, RI 02888.

Abstract

Background. Pseudopelade is a rare idiopathic progressive alopecia that has no initial inflammatory phase. Even so, pseudopelade has been classified as a scarring alopecia with postinflammatory alopecias. Atrophy rather than true scarring is the cardinal feature of pseudopelade.

Materials and Methods. A review of reported cases of pseudopelade, especially those with a family history, was undertaken. The discovery of a young man and his mother, who had pseudopelade, plus two other familial cases prompted this study.

Results. Examination of the clinical and pathologic material shows pseudopelade to be a disease separate from other alopecias. The striking familial association in these cases demonstrates a plausible etiology.

Conclusions. Pseudopelade is an autosomal dominant disorder of the scalp marked by atrophic loss of hair follicles.

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