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Investigation of herpes simplex virus DNA in pityriasis rosea by polymerase chain reaction

Authors

  • Kübra Eren Bozdag MD,

    Corresponding author
    1. From the Department of Dermatology, Atatürk Training and Research Hospital, and the Department of Microbiology and Clinical Microbiology, Ege University Medical Faculty, Izmir, Turkey
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  • Füsun Özder Güven MD,

    1. From the Department of Dermatology, Atatürk Training and Research Hospital, and the Department of Microbiology and Clinical Microbiology, Ege University Medical Faculty, Izmir, Turkey
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  • Aysin Zeytinoglu MD,

    1. From the Department of Dermatology, Atatürk Training and Research Hospital, and the Department of Microbiology and Clinical Microbiology, Ege University Medical Faculty, Izmir, Turkey
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  • Selda Erensoy MD,

    1. From the Department of Dermatology, Atatürk Training and Research Hospital, and the Department of Microbiology and Clinical Microbiology, Ege University Medical Faculty, Izmir, Turkey
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  • Ahmet Karaman MD,

    1. From the Department of Dermatology, Atatürk Training and Research Hospital, and the Department of Microbiology and Clinical Microbiology, Ege University Medical Faculty, Izmir, Turkey
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  • Altýnay Bilgiç MD

    1. From the Department of Dermatology, Atatürk Training and Research Hospital, and the Department of Microbiology and Clinical Microbiology, Ege University Medical Faculty, Izmir, Turkey
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Correspondence Kübra Eren Bozdag Mithatpasa Caddesi, No: 388/7 35280-Asansör Izmir Turkey E-mail: bozdag@egenet.com.tr

Abstract

Background  Pityriasis rosea (PR) is an acute, inflammatory disease of unknown cause. Clinical and experimental findings indicate an infectious etiology of PR. Our purpose is to examine the skin lesions and blood samples of PR patients by polymerase chain reaction (PCR) for the presence of HSV type 1 and 2 DNA.

Methods  The lesional skin biopsies from 10 patients and blood samples from two randomized patients with clinically and histologically confirmed pityriasis rosea were examined by PCR.

Results  No HSV 1 and HSV 2 DNA was detected in the lesional biopsy and blood samples.

Conclusions  We could not identify a relationship between HSV 1, HSV 2 and PR.

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