Mycobacterium marinum with different responses to second-generation tetracyclines
Article first published online: 1 JUN 2005
International Journal of Dermatology
Volume 44, Issue 6, pages 518–520, June 2005
How to Cite
Cummins, D. L., Delacerda, D. and Tausk, F. A. (2005), Mycobacterium marinum with different responses to second-generation tetracyclines. International Journal of Dermatology, 44: 518–520. doi: 10.1111/j.1365-4632.2005.02204.x
- Issue published online: 1 JUN 2005
- Article first published online: 1 JUN 2005
Background Persistent cutaneous infections with Mycobacterium marinum can follow exposure of injured skin to contaminated water or fish, and can be treated with second-generation tetracyclines in addition to other antimicrobials. Due to the rarity of this infection, there are few data comparing the different treatment alternatives.
Methods We report a patient with culture-proven M. marinum who was treated with two different second-generation tetracyclines.
Results Our patient failed a 4-week trial of doxycycline, but responded rapidly to minocycline.
Conclusion This case suggests that, despite a similar mechanism, pharmacokinetics, and even sensitivity, these two agents may differ in their effectiveness against strains of M. marinum.