This paper was approved by the Ethics Committee on research of the participating hospitals, assuring the patients confidentiality of the obtained results.
Seroprevalence of HHV-8 infection in the pediatric population of two university hospitals in Rio de Janeiro, Brazil
Article first published online: 17 JAN 2006
International Journal of Dermatology
Volume 45, Issue 4, pages 381–383, April 2006
How to Cite
Avelleira, J. C. R., Lupi, O., Caterino-de-Araujo, A. and Santos-Fortuna, E. d. l. (2006), Seroprevalence of HHV-8 infection in the pediatric population of two university hospitals in Rio de Janeiro, Brazil. International Journal of Dermatology, 45: 381–383. doi: 10.1111/j.1365-4632.2006.02523.x
- Issue published online: 5 APR 2006
- Article first published online: 17 JAN 2006
Background The authors present a serologic survey of the prevalence of herpesvirus-8 (HHV-8) among 171 children from 0 to 12 years old in Rio de Janeiro, Brazil.
Materials and methods Sera were tested for latent nuclear and lytic antigens using indirect immunofluorescence and Western blotting.
Results Serology for HHV-8 was positive in 16 of 171 patients (9.35%). Among 13 HIV-positive patients, four (31%) were also positive for HHV-8. The seropositivity among healthy children was 7.6%, and females were significantly (P < 0.002) more associated with HHV-8 seropositivity (16%) than males (1.1%).
Conclusions We detected a higher HHV-8 seroprevalence among the pediatric population in Rio de Janeiro, Brazil, when compared with similar studies performed in other countries. Nonsexual routes of transmission are a possible explanation for this pattern. The unusual finding of a higher seroprevalence among female children could be explained by a specific route of exposition or even an epidemiological bias.