Two cases of Zoon's balanitis treated with pimecrolimus 1% cream
Article first published online: 15 JAN 2008
© 2008 The International Society of Dermatology
International Journal of Dermatology
Volume 47, Issue 2, pages 198–201, February 2008
How to Cite
Bardazzi, F., Antonucci, A., Savoia, F. and Balestri, R. (2008), Two cases of Zoon's balanitis treated with pimecrolimus 1% cream. International Journal of Dermatology, 47: 198–201. doi: 10.1111/j.1365-4632.2008.03392.x
- Issue published online: 15 JAN 2008
- Article first published online: 15 JAN 2008
Background Plasma cell balanitis is a disorder of the middle-aged and older uncircumcised male. Several treatments have been proposed to treat this disease, but plasma cell balanitis is often resistant to conventional therapy.
Methods We decided to evaluate the efficacy and tolerability of pimecrolimus 1% cream in resistant Zoon's balanitis. We report two cases of resistant Zoon's balanitis treated with topical pimecrolimus 1% cream.
Results One of the two patients had a complete regression of the lesion after 2 months of therapy. The other one had a great improvement of the lesion, but a hyperpigmented patch persisted on the glans.
Conclusion Pimecrolimus 1% cream may be a valuable second-line treatment for patients with steroid related side effects or with steroid and other conventional therapy resistant Zoon's balanitis, as well as for those rejecting circumcision.