Neutrophilic dermatosis of the hands after influenza vaccination
Article first published online: 28 DEC 2008
© 2009 The International Society of Dermatology
International Journal of Dermatology
Volume 48, Issue 1, pages 66–68, January 2009
How to Cite
Wolf, R., Barzilai, A. and Davidovici, B. (2009), Neutrophilic dermatosis of the hands after influenza vaccination. International Journal of Dermatology, 48: 66–68. doi: 10.1111/j.1365-4632.2009.03897.x
- Issue published online: 28 DEC 2008
- Article first published online: 28 DEC 2008
An otherwise healthy 72-year-old man presented with a painful eruption composed of grouped hemorrhagic purulent blisters on erythematous plaques, on both palms of his hands, which appeared 12 h after he had been vaccinated against influenza.
Based on the patient's history, physical examination, histopathological and laboratory findings, the diagnosis of neutrophilic dermatosis of the hands (NDH) was made.
NDH is currently considered a distributional variant of Sweet's syndrome (SS). It is identical to atypical pyoderma gangrenosum (PG) and pustular vasculitis of the hands.
There are only seven reported cases of SS after vaccination, none of them with lesions confined solely to the palms or soles. Our current case is the third one of SS following influenza vaccination.