Itch pathophysiology may differ among ethnic groups


  • Funding: None.

  • Conflicts of interest: None.

Enes Hajdarbegovic, md
Department of Dermatology and Venereology
Erasmus Medical Centre
Burgemeester’s Jacobplein 51
3015 NL Rotterdam
the Netherlands


The prevalence of itch is higher in individuals with darker skin types. In this paper, we review the systems involved in the physiology of itch and how they may differ across the races. Current data point out that the differences may be explained by barrier function, mast cell physiology, and itch receptor polymorphisms.