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International guidelines for clinical trials with pediculicides


  • Financial disclosure: none.

Dr Stephen C. Barker, phd
Parasitology Section
School of Chemistry and Molecular Biosciences
The University of Queensland
Queensland 4072


Pediculosis capitis, infestation with head lice, is common in all human societies. Chemical pediculicides are often used to control head louse infestations, particularly in wealthy communities. A significant number of different protocols have been used to test the efficacy and safety of pediculicides in clinical trials; this constrains scientific comparison of the evidence for efficacy of the different pediculicides. Here we recommend protocols for clinical trials of the efficacy and safety of single-, two-, and three-treatment interventions.